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Research Interests:Work in the Claridge-Chang laboratory is aimed at understanding cognitive and emotional behaviors using the Drosophila melanogaster model system, elucidating the neurogenetic mechanisms that underlie aversive olfactory learning and defensive behaviors. We develop and apply a range of genetic, physiological and behavioral methods to understand how locomotion and other actions play a role in the learning process. Selected Publications:Claridge-Chang A, Roorda RD, Vrontou E, Sjulson L, Li H, Hirsh J, Miesenböck G. 2009 Writing memories with light-addressable reinforcement circuitry. Cell, 139(2), pp. 405-15. Shang Y, Claridge-Chang A, Sjulson L, Pypaert M, Miesenböck G. 2007. Excitatory local circuits and their implications for olfactory processing in the fly antennal lobe. Cell, 128 (3), pp. 601-12. Wijnen H, Naef F, Boothroyd C, Claridge-Chang A, Young MW. 2006. Control of daily transcript oscillations in Drosophila by light and the circadian clock. PLoS Genetics, 2 (3), pp. e39. Claridge-Chang A, Wijnen H, Naef F, Boothroyd C, Rajewsky N, Young MW. 2001. Circadian regulation of gene expression systems in the Drosophila head. Neuron, 32 (4), pp. 657-71. |
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