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NEUROSC Key Appointment Holders

Louis Tan Chew Seng

Clinical Professor

Vice Chair, Research, Neuroscience Academic Clinical Programme

Deputy Director, Research, National Neuroscience Institute


Education Qualifications: MBBS (Singapore), MRCP (United Kingdom), FAMS (Neurology), FRCP (Edinburgh)

Dr Louis Tan is a Co-Director of its Parkinson’s Disease and Movement Disorders Centre (TTSH campus) and an Adjunct Professor of Duke-NUS Graduate Medical School, Singapore.

He is Treasurer (2019 to 2021) of the International Parkinson and Movement Disorder Society and previously served as Chair of the Education committee and Asian-Oceanian Section of the Society.  

Upon graduating from the National University of Singapore and completing his neurology training at Tan Tock Seng Hospital, he underwent a movement disorders fellowship at the Parkinson’s Institute in Sunnyvale, California. 

His areas of specialty and research interests are Parkinson’s disease and movement disorders. He is also interested in the epidemiology, clinical studies and clinical trials in Parkinson’s disease and other movement disorders.

Professional Appointments and Committee Memberships:

  • Senior Consultant, Department of Neurology, National Neuroscience Institute
  • Treasurer, International Parkinson and Movement Disorder Society
  • Co-Director, Parkinson’s Disease and Movement Disorders Centre, USA National Parkinson Foundation, International Centre of Excellence 
  • President, Parkinson Society Singapore


  • Dean’s Award for teaching excellence AY 2013/14, Yong Loo Lin School of Medicine, National University of Singapore
  • Distinguished Team Award (team lead), Singhealth Excellence Award 2015
  • President’s Distinguished Service Award 2015.  International Parkinson and Movement Disorders Society
  • Singapore Health Quality Service Award 2016, Silver
  • Distinguished Member Award.  The Japanese Society of Neurology. 57th Annual Meeting, 2016
  • President’s Science Award, Team award, Singapore, 2018

Leadership positions / roles in Education: 

  • Clinical Core Faculty Member, SingHealth Residency Programme
  • Chair of Education committee of the Movement Disorders Society (2011-2013)

Research Interests: Parkinson Disease and Movement Disorders

Selected Publications:

Wen MC, Ng SY, Heng HS, Chao YX, Chan LL, Tan EK, Tan LC.  Neural substrates of excessive daytime sleepiness in early drug naïve Parkinson's disease: A resting state functional MRI study.  Parkinsonism Relat Disord. 2016 Mar;24:63-8.

Tan LC, Methawasin K, Tan EK, Tan JH, Au WL, Yuan JM, Koh WP.  Dietary cholesterol, fats and risk of Parkinson's disease in the Singapore Chinese Health Study.  J Neurol Neurosurg Psychiatry. 2016 Jan;87(1):86-92.

Linda P. Oosterveld, John C. Allen Jr, Ebonne Y.L. Ng, Soo-Hoon Seah , Kay-Yaw Tay, Wing-Lok Au, Eng-King Tan,  Louis C.S. Tan.  Greater motor progression in Parkinson’s disease patients with LRRK2 risk variants.  Neurology. 2015 Sep 22;85(12):1039-42. 

YJ Zhao, HL Wee, YH Chan, SH Seah, WL Au, PN Lau, EC Pica, SC Li, N Luo and LCS Tan.  Progression of Parkinson’s Disease as Evaluated by Hoehn and Yahr Stage Transition Times.  Mov Disord 2010; 25(6):710-716.

LCS Tan, N Venketasubramanian, CY Hong, S Sahadevan, JJ Chin, ES Krishnamoorthy, AKY Tan, SM Saw.  Prevalence of Parkinson’s disease in Singapore: Chinese vs Malays vs Indians.  Neurology 2004; 62:1999-2004.