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PAEDS Key Appointment Holders

Derrick Chan Wei Shih

Associate Professor

Programme Director, Clinician - Innovator Development Programme (CINDP)

Vice Chair, Research, Paediatrics Academic Clinical Programme

Research Director, KK Research Centre


Education Qualifications: BMedSci, BMBS, MRCPCH, MCI, CSCN, FAMS

Dr Chan graduated from Nottingham University with Bachelor’s in Medical Science (1996) and Bachelor of Medicine and Surgery (1998), passed his Membership exams for the Royal College of Paediatrics and Child Health in 2002 and obtained Specialist Accreditation in Paediatric Medicine in 2007. He is trained in Paediatric EEG at Great Ormond Children's Hospital in London, UK and the Royal Children’s Hospital in Melbourne, followed by a 15-month Clinical Fellowship in Paediatric Epilepsy at the Hospital for Sick Children in Toronto. 

Dr Chan obtained certification in Clinical Neurophysiology from the Canadian Society of Clinical Neurophysiology in 2008 and received his Master’s Degree in Clinical Investigation in 2011. 

He set up the comprehensive epilepsy programme at KKH, including the epilepsy monitoring unit, ketogenic diet and complicated epilepsy clinics, vagus nerve stimulator implantation programme and epilepsy surgery programme. He is driving the paediatric epilepsy research programme and have established collaborations in Paediatric Epilepsy with Duke Durham. He has led the Paediatric Neurology team to clinical, research and educational excellence, expanding the team and establishing expertise in vital areas of paediatric neurology. Under his mentorship, this team spearheads in clinical care, research, education and medical informatics. 

Dr Chan has raised Paediatric Neurology at KKH to world-class standards, with trainees applying from the ASEAN region, Africa, the Middle East and Europe and recognition from Australia and the United Kingdom as a training centre. He mentored the KKH/Singhealth team for the 2017 Health Service Development Programme grant “PINS: Paediatric Integrated Neurorehabilitation Service – Integrating tertiary and community care”, which has been selected for funding in 2018.

Professional Appointments and Committee Memberships:

  • Head & Senior Consultant, Neurology Service, KK Women's and Children's Hospital
  • Adjunct Assistant Professor, Yong Loo Lin-NUS School of Medicine
  • Adjunct Associate Professor, Lee Kong Chian School of Medicine
  • Fellow, Academy of Medicine, Singapore
  • Fellow, Royal College of Pediatrics and Child Health (RCPCH)


  • National Service Excellence Award, Singapore Armed Forces (2018)
  • Singhealth Long Service Award (2015)
  • Singapore Health Quality Service Award (Star) (2014)
  • KK People Developer Award: Outstanding Clinical Teacher (2012)
  • Best Poster (Medical) KKH ASM (2011)
  • Best Teacher (Residents & Fellows), Hospital for Sick Children, Toronto, Ontario (2008)
  • Merit Award, Free Paper Competition, 2nd KKH Annual Scientific Meeting (2007)
  • SingHealth HMDP Fellowship in in Paediatric Epilepsy and Neurology (2007)
  • EXSA Silver Award (2006)

Leadership positions / roles in Education: 

Research Interests: Paediatric Epilepsy, Quantitative analysis of electroencephalography and Pharmacogenomics of anticonvulsant adverse reactions

Selected Publications:

Underutilization of epilepsy surgery in ASEAN countries.Thuy Le MA, Fong SL, Lim KS, Gunadharma S, Sejahtera DP, Visudtibhan A, Chan D, Vorachit S, Chan S, Ohnmar, Chua AE, Cabral-Lim L, Yassin N, Le VT, Tan CT. Seizure. 2019 Jul;69:51-56. doi: 10.1016/j.seizure.2019.04.002. Epub 2019 Apr 4.

Utility of the Seattle Heart Failure Model for palliative care referral in advanced ambulatory heart failure. Ng Fat Hing N, MacIver J, Chan D, Liu H, Lu YTL, Malik A, Wang VN, Levy WC, Ross HJ, Alba AC. BMJ Support Palliat Care. 2018 Dec 6. pii: bmjspcare-2018-001626. doi: 10.1136/bmjspcare-2018-001626. [Epub ahead of print]

Review of clinical studies of perampanel in adolescent patients. Kim HD, Chi CS, Desudchit T, Nikanorova M, Visudtibhan A, Nabangchang C, Chan DW, Fong CY, Chang KP, Kwan SY, Reyes FL, Huang CC, Likasitwattanakul S, Lee WT, Yung A, Dash A. Brain Behav. 2016 Jun 28;6(9):e00505. eCollection 2016 Sep. 

Serial outcomes in acute necrotising encephalopathy of childhood: A medium and long term study. Lim HY, Ho VP, Lim TC, Thomas T, Chan DW. Brain Dev. 2016 Nov;38(10):928-936. doi: 10.1016/j.braindev.2016.05.002. Epub 2016 May 30.

Guiding follow-up of paediatric idiopathic intracranial hypertension with optical coherence tomography. Loo KG, Lim SA, Lim IL, Chan DW. BMJ Case Rep. 2016 Mar 3;2016. pii: bcr2015213070. doi: 10.1136/bcr-2015-213070.

Neurology of the H1N1 pandemic in Singapore: a nationwide case series of children and adults Prerna A, Lim JY, Tan NW, Isa MS, Oh HM, Yassin N, Low CY, Chan DW, Chong CY, Leo YS, Chow AL, Tambyah PA, Tan K. J Neurovirol. 2015 Oct;21(5):491-9. doi: 10.1007/s13365-015-0341-3. Epub 2015 Apr 28.

Use of Magnesium Sulfate Infusion for the Management of Febrile Illness-Related Epilepsy Syndrome: A Case Series. Tan WW, Chan DWS, Lee JH, Thomas T, Menon AP, Chan YH. Child Neurol Open. 2015 Mar 23;2(1):2329048X14550067. doi: 10.1177/2329048X14550067. eCollection 2015 Jan-Mar.

Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation (ROHHAD) syndrome may have a hypothalamus-periaqueductal gray localization. Chow C, Fortier MV, Das L, Menon AP, Vasanwala R, Lam JC, Ng ZM, Ling SR, Chan DW, Choong CT, Liew WK, Thomas T. Pediatr Neurol. 2015 May;52(5):521-5. doi: 10.1016/j.pediatrneurol.2014.11.019. Epub 2015 Feb 4.

Association of carbamazepine-induced severe cutaneous drug reactions and HLA-B*1502 allele status, and dose and treatment duration in paediatric neurology patients in Singapore. Chong KW, Chan DW, Cheung YB, Ching LK, Hie SL, Thomas T, Ling S, Tan EC. Arch Dis Child. 2014 Jun;99(6):581-4. doi: 10.1136/archdischild-2013-304767. Epub 2013 Nov 13.

Tocilizumab attenuates inflammation in ALS patients through inhibition of IL6 receptor signaling. Mizwicki MT, Fiala M, Magpantay L, Aziz N, Sayre J, Liu G, Siani A, Chan D, Martinez-Maza O, Chattopadhyay M, La Cava A. Am J Neurodegener Dis. 2012;1(3):305-15. Epub 2012 Nov 21.