Jafar, Tazeen H

MBBS, MPH, FNKF

Professor

Health Services & Systems Research Programme

Other Affiliations:

Aga Khan University

+65 6601 2582

+65 6534 8632

Email 1:

tazeen.jafar@duke-nus.edu.sg

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Research

Research Interest:

Dr. Jafar¹s research interests include policy-relevant implementation research on chronic non-communicable disease, and epidemiological studies likely to influence clinical practice. Dr Jafar is a US Board certified Nephrologist. Dr Jafar has led many collaborative projects including the individual patient data meta-analysis of 11 internationally conducted randomized controlled trials on Angiotensin Converting Enzyme inhibitors on progression of non-diabetic kidney disease. Funded by the NIH, Dr Jafar has extensive experience of analyzing national health survey data including comparative studies of National Health Survey of Pakistan and US- National Health and Nutrition Examination Survey (NHANES). In Pakistan, Dr Jafar and her collaborators from the UK, established an extensive program of chronic diseases including the Control of Blood Pressure & Risk Attenuation (COBRA) trial evaluating the role of non-physician health workers and physician training on management of hypertension in low and middle income communities, and several projects related to life style (diet, obesity and physical activity) and chronic disease in children and adults. Dr Jafar has mentored several trainees in research, and facilitated the acquisition of competitive research training grants. She serves on a number of editorial boards of scientific journals, and on international advisory panel of Public Library of Science, and is a member of Wellcome Trust's Global Health Trials funding committee. Dr Jafar also advises the government and other agencies on chronic disease related policies, and served as an invited panelist at the Interactive Civil Society Hearing at the 2011 UN Summit on Non-communicable Diseases in New York.

Selected Publications:

Jafar TH, Islam M, Bux R, Poulter N, Hatcher J, Chaturvedi N, Ebrahim S, Cosgrove P. Cost-effectiveness of community-based strategies for blood pressure control in a low-income developing country: findings from a cluster-randomized, factorial-controlled trial. Circulation.2011. 124(15):1615-1625.

Jafar TH, Islam M, Hatcher J, Hashmi S, Bux R, Khan A, Poulter N, Badruddin S, Chaturvedi N. Community based lifestyle intervention for blood pressure reduction in children and young adults in developing country: cluster randomised controlled trial. BMJ.2011. 340:c2641.

Jessani S, Levey AS, Chaturvedi N, Jafar TH. High normal levels of albuminuria and risk of hypertension in Indo-Asian population. Nephrol Dial Transplant.2011

Almas A, Jafar TH. Adiposity and blood pressure in South Asian children and adolescents in Karachi. Am J Hypertens.2011. 24(8):876-880.

Rizwan A, Akhter J, Jafar TH. The association of sugar-sweetened beverage consumption and inadequate physical activity with overweight and obesity in school-going children and adolescents in Pakistan. Arch Dis Child.2010. 96(1):109-111.

Jafar TH, Hatcher J, Poulter N, Islam M, Hashmi S, Qadri Z, Bux R, Khan A, Jafary FH, Hameed A, Badruddin SH, Chaturvedi N. Community-based interventions to promote blood pressure control in a developing country: a cluster randomized trial. Ann Intern Med. 2009;151(9):593-601.

Jessani S, Hatcher J, Chaturvedi N, Jafar TH. Effect of low vs. high dietary sodium on blood pressure levels in a normotensive Indo-Asian population. Am J Hypertens. 2008;21(11):1238-1244.

Qureshi NN, Hatcher J, Chaturvedi N, Jafar TH. Effect of general practitioner education on adherence to antihypertensive drugs: cluster randomised controlled trial. BMJ. 2007;335(7628):1030.

Jafar TH. The growing burden of chronic kidney disease in Pakistan. N Engl J Med. 2006;354(10):995-997.

Jafar TH, Islam M, Poulter N, Hatcher J, Schmid CH, Levey AS, Chaturvedi N. Children in South Asia have higher body mass-adjusted blood pressure levels than white children in the United States: a comparative study. Circulation. 2005;111(10):1291-1297.

Jafar TH, Stark PC, Schmid CH, Landa M, Maschio G, de Jong PE, de Zeeuw D, Shahinfar S, Toto R, Levey AS. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med. 2003;139(4):244-252.

Jafar TH, Schmid CH, Landa M, Giatras I, Toto R, Remuzzi G, Maschio G, Brenner BM, Kamper A, Zucchelli P, Becker G, Himmelmann A, Bannister K, Landais P, Shahinfar S, de Jong PE, de Zeeuw D, Lau J, Levey AS. Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease. A meta-analysis of patient-level data. Ann Intern Med. 2001;135(2):73-87.

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