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MD & MD/PhD

Cardiovascular & Metabolic Disorders

The CVMD programme houses state-of-the-art research capabilities, including core facilities for profiling mitochondrial function (e.g. oxygen consumption, ATP production, etc.) and metabolic adaptations (e.g. indirect calorimetry, euglycemic clamps, etc.) in human patients and other model organisms. Moreover, its new Metabolomics Facility allows one to obtain both targeted and non-targeted profiles of nutrient metabolites (e.g. fatty acids, amino acids, citric acid cycle intermediates, etc.) using mass spectroscopy. Application of these technologies allows one to gain a strong appreciation of the metabolic dysregulation that serves as an underpinning for cardiovascular and metabolic diseases.

As part of the training regimen, CVMD students will conduct independent research under the tutelage of one of our world-class research scientists. Moreover, they will take advanced coursework on molecular cardiovascular biology and integrated metabolism. Students trained in this programme will be on a path to become independent investigators running independent research programs in industry or academia.

For more information on how to apply to the PhD Program, click here.

Please listen to our PI lab project presentations for more information: 
http://teamlead.duke-nus.edu.sg/vapfiles_ocs/2011/research_week/srp/cvmd_research/ 
(Note: VAP presentation is best viewed at Google Chrome browser)


Name Research Topic Lab Email Contact
Silver, David L
Professor

Diabetes, lipid metabolism, regulation of energy homeostasis, membrane proteins

Duke-NUS

david.silver@duke-nus.edu.sg

+65 6601 2172
Yen, Paul M
Professor

Thyroid function; nuclear hormone receptor; hepatic steatosis; PI3-kinase and cancer

Duke-NUS

paul.yen@duke-nus.edu.sg

+65 6516 7332
Sun, Lei
Assistant Professor

Noncoding RNA's in Brown Fat

Duke-NUS

sun.lei@duke-nus.edu.sg

+65 6601 3021


Kovalik, Jean-Paul

Assistant Professor

Mitochondrial fuel flux in fat cells

Duke-NUS

jean-paul.kovalik@duke-NUS.edu.sg

+65 6601 3144
Cook, Stuart
Professor

Genetic cardiomyopathy, heart failure, stroke, myocardial insulin resistance, genetic regulation of cardiac arrhythmias.

Duke-NUS

stuart.cook@duke-nus.edu.sg

+65 6601 2584

Petretto, Enrico
Associate Professor

Systems-genetics and network biology, genetical genomics and bioinformatics, identification of functional gene targets in cardio-metabolic, fibrotic, inflammatory and neuropsychiatric diseases.

Duke-NUS

enrico.petretto@duke-nus.edu.sg

+65 6601 5114

Hausenloy, Derek
Professor

Acute myocardial ischemia/reperfusion injury, Cardioprotection (basic science and clinical), Cardiac imaging, Heart failure, Intracellular signalling, Mitochondrial function.

Duke-NUS

derek.hausenloy@dke-nus.edu.sg

+ 65 6601 5121

Singh, Manvendra
Assistant Professor

Cardiovascular Development, Congenital Cardiac Diseases, Ischemic Heart Disease, Cardiac Metabolism in Heart Failure.

Duke-NUS

manvendra.singh@duke-nus.edu.sg

+65 6601 3098

Lena Ho
Assistant Professor

Small ORF-derived peptides, angiocrines, myokines, proteogenomics, vascular biology.

Duke-NUS

lenaho@duke-nus.edu.sg

+65 66016236