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Cancer Resistance in Asians: A Genetic Cause Found

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A multi-national team led by Duke-NUS Associate P rofessor Ong Sin Tiong successfully identified a gene mutation occurring in about 15% of East Asian populations as the underlying cause to why some blood and lung cancer patients failed to benefit from existing cancer medication. Not only did Assoc. Prof. Ong’s team uncover the defective gene, they also identified a novel class of drugs as the solution for such drug resistance. This discovery has the potential to benefit or extend the survival of more than 15,000 affected patients worldwide per year.

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