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Chronic/Complex Diseases

Health Services and Systems Research (HSSR) Singapore Chronic/Complex Diseases

As in economically advanced countries with relatively young populations, Singapore has successfully focused on and developed high-quality acute-care hospitals and affiliated services. With the aging population, however, the challenge is to address the needs of many more individuals with complex and chronic diseases, and to do it in a way that is both financially sustainable and consistent with the ethos of maintaining personal responsibility.


In addition to the work described in the section on Aging and Long-term Care in which our focus is on the potential of integrated services to address the needs of individuals with common chronic diseases, we are studying needs and potential solutions to the problems of coordinating stroke care from the acute event through rehabilitation. In addition, we are using evidence-based yet resource-efficient strategies for reducing the risk of falls in the elderly. As with the other implementation projects described here, a major early goal is establishing a foundation of high-quality, community-based implementation studies.

Chronic/Complex Diseases Projects

Study of the Impact of Caregiving for Stroke Survivors on Family Structure and the Mental Health of Caregivers

Description: Stroke is a common disabling disease that often results in permanent physical, cognitive and emotional changes for the survivors. The impact of stroke on the caregivers and the importance of interventions have been well-studied. Well planned intervention programmes within the community aimed at giving support to the caregivers can minimize caregiving burden and...

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Singapore Infragenicular Angioplasty with Paclitaxel-eluting balloon for Critical Limb Ischaemia (SINGA-PACLI) Trial

Description: Critical limb ischemia (CLI) leads to significant morbidity and mortality, and consumption of substantial health and social care resources in both developed and developing countries.1 Without treatment, patients with CLI are at risks of amputations, and potentially lethal complications such as sepsis. In many centers, endovascular therapy by percutaneous...

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A Randomized Controlled Trial to Improve the Uptake of and Adherence to Outpatient Rehabilitation Services among Stroke Patients

Stroke is the leading cause of long-term disability in Singapore, and specialized stroke rehabilitation can help stroke patients regain their post-stroke functions. However, despite the benefits associated with using the rehabilitation services, only 33% of the stroke patients in Singapore take up the stroke outpatient rehabilitation services (ORS). According to local longitudinal studies,...

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A single arm feasibility study of Glyco Leap, an on-line lifestyle modification and self-management program for people with Type 2 diabetes

Background: Over the last 30 years, there has been a rapid rise in the number of people with diabetes, especially type 2 diabetes. Singapore has the second-highest proportion of people with diabetes among developed nations - at 10.53 per cent of people aged between 20 and 79, according to a report from the International Diabetes Federation. An equally worrying trend is that,...

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A Randomized Trial to Slow the Progression of Diabetes (The TRIPOD study)

A primary focus of the ‘Diabetes’ theme is to identify new models to arrest the rate of deterioration and reduce acute episodes for those with diabetes, and to do so in a cost-effective manner while incorporating elements of secondary and tertiary care aligned with primary prevention efforts. This proposal is highly responsive to those objectives. We will conduct a three arm randomized...

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