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“To work on the discovery of photographic memory that can retain whatever is seen, heard, or sensed, and which can never be forgotten.”

“YES!!!” is the answer whenever someone asks about our research.

Bats have commonly been associated with evil (e.g. Dracula) and the dark side of things in western cultures. Their reputation as terrors of the night and vicious blood suckers have haunted many of us since our childhood. Halloween will never be complete without a bat or two hanging around as decorations. But on the other side of the world, sightings or association with bats are considered auspicious omens in Chinese culture. This is mainly due to the Chinese word for “Bats (Fú)” being a homonym to the Chinese word for “Fortune (Fú)”.

Antonius Van DongenAssociate Professor Antonius Van Dongen of the Neuroscience and Behavioural Disorders Programme at Duke-NUS Medical School is also Director of the SingHealth Advanced Bioimaging Core.Today, Dr Van Dongen shares with us more about microscopy and the Core's advanced bioimaging capabilities available to SingHealth and Singapore investigators.

Shee-Mei Lok

 

Shee-Mei Lok is a structural biologist and an Associate Professor in the Emerging Infectious Diseases Programme at Duke-NUS Medical School, who specialises in studying the structure of flaviviruses such as dengue in order to find and exploit ways to weaken them. This year Prof Lok was at the forefront of Zika virus research in Singapore as she uncovered important details about the virus' structure, which gave hope and arsenal to the researchers and scientists working to counter it. The National Research Foundation (NRF) recently featured Prof Lok's personal and academic journey in NRF's Scientists Profiles, which you can read here

Prof Eric FinkelsteinNamed one of the World’s Most Influential Scientific Minds of 2015 by Thomson Reuters, Prof Finkelstein has an impressive list of over 160 publications to his name, with an even more impressive 15,000 citations.Eric Finkelstein is Director of Lien Centre for Palliative Care, and Professor of the Health Services and Systems Research Programme at Duke-NUS Medical School.

Catch up on the highlights of the recent SingHealth Duke-NUS Scientific Congress 2016!

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Calling for your images of resarch!

Send your images of research to microscope@duke-nus.edu.sg.

Dr Gerald Liew received his PhD in Biochemistry from Stanford University, and is currently a first year MD student at Duke-NUS Medical School. His primary research interest investigates the signalling pathways involved in ensuring proper primary cilium function. Today, Gerald shares with us more about this topic from his PhD Thesis.

Psychedelic cerebrum

 

A coronal section of a mouse brain is set ablaze with the fluorescent glow of different markers. Myelin in green, axons in red, microglia in magenta and nuclei in blue brings the structure of the hippocampus, striatum, thalamus and hypothalamus into focus.

 Image by Chan Jia Pei, PhD student in the laboratory of Professor David Silver
Cardiovascular and Metabolic Disorders Programme
Duke-NUS Medical School

 

Julien Pompon, molecular entomologist and Assistant Professor in the Emerging Infectious Diseases Programme at  Duke-NUS Medical School shines a light on his work with mosquitoes and what attracts and repels these pesky (but resilient) insects.

MosquitoHow do you test for behaviour in mosquitoes?

We observe mosquito behaviour primarily while they feed, which corresponds to the transmission phase. Mosquitoes are observed in real time by a researcher who rates their behaviour - such as the mosquito’s landing, insertion of the proboscis, imbibing of blood, number and time of each probe, etc. Real-time behaviour is then used to compute several important parameters that help us to assess the impact of different factors on mosquito biting success.

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