A Research Blog

Mosquitoes

Dengue and chikungunya are mosquito-borne diseases that are currently re-emerging as public health burdens worldwide. Annually, over 390 million people are infected with dengue, while chikungunya periodically emerges in highly populated areas. The primary vector for the two diseases is Aedes aegypti, a mosquito that thrives in domestic areas.

 Since there is no vaccine for these arboviruses, vector control remains the best way to control the incidence of these diseases. In the 1960s, the Singapore government started a vector control campaign in order to prevent the transmission of dengue by Aedes aegypti. Measures included mosquito and clinical surveillance, public health education, community participation, fines for allowing mosquito breeding, among others. While this campaign drastically reduced the number of households with Aedes mosquitoes and the incidence of dengue in Singapore until the 1990s, dengue epidemics have since increased in frequency, and chikungunya re-emerged in 2008.

 To better understand this paradoxical situation Principal Research Scientist Ian Mendenhall and Assistant Professor Julien Pompon from Duke-NUS Medical School (Duke-NUS) led research that investigated whether peridomestic areas, or areas near inhabited areas, could be the cause or source of these diseases.

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