In this issue of MEDICUS, special In Conversation With guest host Duke-NUS Dean Thomas Coffman speaks to the presidents of Duke-NUS’ parent universities—Duke University and the National University of Singapore (NUS). In this two-part special, Duke President Vincent E Price and NUS President Tan Eng Chye and share their perspectives on how the pandemic has impacted university communities, what the future of learning and higher education will look like and how they cope with the responsibilities and demands of leading a top global institution.