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NBD Seminar Series: NeuroD1 AAV-Based Neuroregenerative Gene Therapy for Brain Repair (via Zoom)
Abstract:
We have pioneered an in vivo astrocyte-to-neuron conversion technology to regenerate functional new neurons using internal reactive astrocytes. In this talk, I will discuss our recent progress in developing AAV NeuroD1-based neuroregenerative gene therapy to treat a variety of neurological disorders. We found that NeuroD1 treatment not only generated functional neurons that integrated into neuronal circuits but also facilitated functional recovery in animal models.
Join Zoom Meeting
https://nus-sg.zoom.us/j/86815324715?pwd=cDE2L2l5elhQY3FJOW1ETDZDbmUzQT09
Meeting ID: 868 1532 4715
Passcode: 232607
Host:
Prof Zhang Suchun
Programme Director
Neuroscience & Behavioural Disorders Programme, Duke-NUS
Contact Person:
Joyceline Ng (joyceline.ng@duke-nus.edu.sg)
Neuroscience & Behavioural Disorders Programme, Duke-NUS
All are welcome, no registration is required.
Date and Time
24 Sep 2021 @ 10:00 - 24 Sep 2021 @ 11:00
Speaker
Prof Gong Chen
Director of Brain Repair Center
GHM Institute of CNS Regeneration
Jinan University
Gong Chen was Verne M. Willaman Chair Professor at Penn State University, and now Director of Brain Repair Center at Jinan University, Guangzhou, China. Dr. Chen pioneered an innovative in vivo reprogramming technology, converting reactive glial cells directly into functional neurons in situ. He is now focusing on translational research in non-human primate models and developing neuroregenerative gene therapy for future clinical trials. Dr. Chen filed >100 patent applications, with >30 issued.