Centre for Computational Biology



Chen Huimei

Principal Research Scientist, Centre for Computational Biology

Duke-NUS Medical School

Bio

With a strong foundation in medicine and physiology, my research endeavors are centered on unraveling the underlying mechanisms of complex diseases and developing innovative therapeutic strategies. I have recently integrated system genetics into my studies, employing a multi-omics approach to identify target genes and pathways. This has facilitated progress in mechanistic and preclinical studies using mouse models. To date, I have identified numerous risk genes associated with diabetes, obesity, kidney diseases, and cardiovascular conditions, and have thoroughly investigated these genes' roles in addressing these diseases.

Moving forward, my research will continue to concentrate on the complexities of chronic diseases, particularly tissue fibrosis. I plan to enhance our understanding of these conditions by integrating multi-omics research approaches. Beyond data integration and analysis, I intend to leverage advanced computational models and deep learning techniques to decipher disease mechanisms at a systemic level. The ultimate goal of my research is to translate these scientific findings into clinical applications. By establishing robust preclinical models and utilizing cutting-edge analytical techniques, I aim to accelerate the development of effective therapeutic interventions.

Education

Doctor of Philosophy (Physiology)

Nanjing University, China

NUS Appointment(s)

Senior Research Fellow/Principal Research Scientist

Duke-NUS Medical School, Currently Active

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