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Centre for Computational Biology

Olona Ferrer Antoni Maria

Research Fellow


Contact: 66018212

Toni graduated with a Bachelor in Biology and a Masters degree in Genetics from the University of Barcelona in Spain. He then moved to St. George's hospital, University of London, where he gained experience in cell biology and microscopy. He obtained a PhD degree in immunology and metabolism at Imperial College London under the supervision of Jacques Behmoaras. He published his PhD project (Mol. Metab; Br J. Pharmacol) and gained doctoral and post-doctoral knowledge in translational immunology and metabolism by studying macrophage-related pathways such as the inflammasome. Toni has recently joined Jacques Behmoaras' group in the Centre for Computational Biology, Program in Cardiovascular and Metabolic Disorders, Duke-NUS, to carry out translational research on the role of macrophages in ageing and metabolic diseases.

  1. Antoni Olona, Subhankar Mukhopadhyay, Charlotte Hateley, Fernando O. Martinez, Siamon Gordon & Jacques Behmoaras “Adipoclast: a multinucleated fat-eating macrophage” BMC Biol 2021 Nov 19;19(1):246.
  2. Antoni Olona, Charlotte Hateley, Sneha Muralidharan, Markus R Wenk, Federico Torta, Jacques Behmoaras “Sphingolipid metabolism during Toll-like receptor 4 (TLR4)-mediated macrophage activation” British Journal of Pharmacology 2021 Dec;178(23):4575-4587 (First published: 06 August 2021).
  3. Antoni Olona, Charlotte Hateley, Ana Guerrero, Jeong-Hun Ko, Michael R Johnson, Paras K. Anand, David Thomas, Jesus Gil, and Jacques Behmoaras. “Cardiac glycosides cause cytotoxicity in human macrophages and ameliorate white adipose tissue homeostasis” British Journal of Pharmacology 2021 Mar 4.  doi: 10.1111/bph.15423. 
  4. Jeong-Hun Ko, Antoni Olona, Adonia E. Papathanassiu, Norzawani Buang, Kwon-Sik Park, Ana S. H. Costa, Claudio Mauro, Christian Frezza, Jacques Behmoaras. “BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages” Journal of Cell Science, 133: jcs247957; November 27, 2020. 
  5. Ana Guerrero, Nicolás Herranz, Bin Sun, Verena Wagner, Suchira Gallage, Romain Guiho, Katharina Wolter, Joaquim Pombo, Elaine E. Irvine, Andrew J. Innes, Jodie Birch, Justyna Glegola, Saba Manshaei, Danijela Heide, Gopuraja Dharmalingam, Jule Harbig, Antoni Olona, Jacques Behmoaras, Daniel Dauch, Anthony G. Uren, Lars Zender, Santiago Vernia, Juan Pedro Martínez-Barbera, Mathias Heikenwalder, Dominic J. Withers & Jesús Gil. “Cardiac glycosides are broad-spectrum senolytics”.  Nature Metabolism volume 1, pages1074–1088 (2019).
  6. Marie Pereira, Tai-Di Chen, Norzawani Buang, Antoni Olona, Jeong-Hun Ko, Maria Prendecki, Ana S.H. Costa, Efterpi Nikitopoulou, Laura Tronci, Charles D. Pusey, H. Terence Cook, Stephen P. McAdoo, Christian Frezza, and Jacques Behmoaras. “Acute Iron Deprivation Reprograms HumanMacrophage Metabolism and Reduces Inflammation In Vivo”. Cell Reports 28, 498–511July 9, 2019.
  7. Antoni Olona, Ximena Terra, Jeong-Hun Ko, Carme Grau-Bové, Montserrat Pinent, Anna Ardevol, Ana Garcia Diaz, Aida Moreno-Moral, Matthew Edin, David Bishop-Bailey, Darryl C. Zeldin, Timothy J. Aitman, Enrico Petretto, Mayte Blay, and Jacques Behmoaras. “Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis”. Mol Metab. 2018 May; 11: 18–32.
  8. Struan Bourke, Laura Urbano, Antoni Olona, Ferran Valderrama, Lea Ann Dailey, Mark A. Green, "Silica passivated conjugated polymer nanoparticles for biological imaging applications," Proc. SPIE. 2017 Feb; doi: 10.1117/12.2252035