ETC-501 is a Brain Penetrant MNK Kinase Inhibitor that Potentiates TMZ-Induced Senescence and Sensitizes Glioblastoma Cells to Senolytic Therapy.

Nah GSS, Chong YK, Sulaimi FN, Lee KL, Lim SW, Pang QY, Yu M, Neo ZW, Iqbal J, Nacro K, Hill J, Matter A, Yang H, Ang BT, Tang C, Ong ST.

Cancer Res. 2026 Jan 22. doi: 10.1158/0008-5472.CAN-24-4388. Epub ahead of print. PMID: 41570320.

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