Sarcopenia promotes tumorigenesis by disrupting NOTCH-SDC2-regulated biogenesis of muscle-derived extracellular vesicles.

Goh KY, Lee WX, Gou Q, Choy SM, Ong SC, Gopal Krishnan PD, Wang H, Turqueza LRR, Tan QH, Chua K, Li S, Nishiyama J, Harmston N, Tang HW.

Nat Commun. 2026 Apr 27. doi: 10.1038/s41467-026-72410-y. Epub ahead of print. PMID: 42045191.

Link to Paper