Joint Faculty Staff Details

Faculty
Joint Faculty
Joint Faculty Staff Details

Shirin Kalimuddin

Assistant Professor, SingHealth Duke-NUS Medicine Academic Clinical Programme

gmsshik@nus.edu.sg

About

Professional

Research Interests

Publications

Bio

Asst. Prof Shirin Kalimuddin is a Senior Consultant in the Department of Infectious Diseases at Singapore General Hospital, and holds a joint faculty appointment with the Program in Emerging Infectious Diseases at Duke-NUS Medical School. As a physician-scientist trained in infectious diseases, public health, and viral immunology, her research integrates clinical immunology and experimental medicine to advance understanding of the host immune response to viral infections and inform vaccine development. She is particularly interested in the role of cell-mediated immunity in orthoflaviviral infections such as dengue.

Asst. Prof Kalimuddin is a recipient of the National Medical Research Council of Singapore (NMRC) Transition Award (2019), the NMRC Research Training Fellowship (2021), and the NMRC Clinician Scientist Award (2025).

Education

Master of Public Health

Johns Hopkins University, United States

Member, Royal Coll of Physicians

Royal College of Physicians, UK, United Kingdom

Bachelor of Medicine, Bachelor of Surgery

King's College London, United Kingdom

Bio

Education

Master of Public Health

Member, Royal Coll of Physicians

Bachelor of Medicine, Bachelor of Surgery

Professional Appointment(s)

Physician Faculty Member

Consultant

Adjunct Principal Investigator

Assistant Professor

Assistant Professor

Membership

Fellow

Research Interests

Publications

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans.

Early T cell and binding antibody responses are associated with Covid-19 RNA vaccine efficacy onset

Insights into dengue immunity from vaccine trials.

Chronic sequelae complicate convalescence from both dengue and acute viral respiratory illness.

18F-Fluorodeoxyglucose Positron Emission Tomography as a window into human dengue pathophysiology

2015 Epidemic of severe Streptococcus agalactiae sequence type 283 infections in Singapore associated with the consumption of raw freshwater fish: A detailed analysis of clinical, epidemiological, and bacterial sequencing data.

Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore.

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.

A phase II randomized study to determine the safety and immunogenicity of the novel PIKA rabies vaccine containing the PIKA adjuvant using an accelerated regimen.

Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea.

Bio

Education

Master of Public Health

Member, Royal Coll of Physicians

Bachelor of Medicine, Bachelor of Surgery

Professional Appointment(s)

Physician Faculty Member

Consultant

Adjunct Principal Investigator

Assistant Professor

Assistant Professor

Membership

Fellow

Research Interests

Publications

Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans.

Early T cell and binding antibody responses are associated with Covid-19 RNA vaccine efficacy onset

Insights into dengue immunity from vaccine trials.

Chronic sequelae complicate convalescence from both dengue and acute viral respiratory illness.

18F-Fluorodeoxyglucose Positron Emission Tomography as a window into human dengue pathophysiology

2015 Epidemic of severe Streptococcus agalactiae sequence type 283 infections in Singapore associated with the consumption of raw freshwater fish: A detailed analysis of clinical, epidemiological, and bacterial sequencing data.

Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore.

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls.

A phase II randomized study to determine the safety and immunogenicity of the novel PIKA rabies vaccine containing the PIKA adjuvant using an accelerated regimen.

Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea.

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