Abstract:
Many neuropsychiatric disorders share common behavioural and genetic defects, including impairments in memory. One family of proteins that are implicated in a multitude of neuropsychiatric disorders are Cerebellins. Cbln4 specifically presents as an enigma owing to its expression in regions implicated in learning and memory. Deletion of Cbln4 from these circuits revealed its crucial function at synapses and behaviourally, in memory recall, in a circuit specific manner.
Venue:
Room 7C, Level 7
Duke-NUS
Host:
Assoc Prof Hyunsoo Shawn Je
Principal Investigator
Neuroscience & Behavioural Disorders Programme
Duke-NUS
Contact Person:
Jacqueline Ho (jacqueline.ho@duke-nus.edu.sg)
Neuroscience & Behavioural Disorders Programme
Duke-NUS
Date and Time
25 Nov 2022 @ 12:00 - 25 Nov 2022 @ 13:00
Speaker
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Dr Jai S Polepalli
Assistant Professor - Department of Anatomy
Yong Loo Lin School of Medicine, NUS
Principal Investigator - CeLS Neurobiology Program, NUS
Dr Jai is an Assistant Professor in the Department of Anatomy at the Yong Loo Lin School of Medicine, and a Principal Investigator in the Neurobiology Program at NUS. He has a PhD from the University of Queensland where he trained in Pankaj Sah’s lab, and subsequently relocated to Stanford University where he trained with noted leaders in the field - Rob Malenka and Tom Sudhof. His lab studies synaptic and circuit dysfunctions that lead to abnormal cognition. His lab is funded by MOE and NMRC.