Details

Lee Tih-Shih

Professor, Signature Research Programme in Neuroscience & Behavioural Disorders

tihshih.lee@duke-nus.edu.sg

65167461

About

Academic Contributions

Professional

Research Interests

Publications

Bio

I graduated with MD degree from Yale University, and was trained in Neurology and Psychiatry. After successfully completing residency at Yale, I also graduated with a PhD from Yale. Thesis entitled Genomic and pathophysiological characterization of human temporal lobe epilepsy. My focus was on surgically obtained human brain tissue.

I hold current and unrestricted medical licenses and specialist accreditations in Singapore, US and Canada. After a subspecialty fellowship in Neuropsychiatry, I obtained sub-specialty certification in Neuropsychiatry and Behavioral Neurology.

I am board certified in USA (American Board of Psychiatry and Neurology), Fellow of the Royal College of Physicians of Canada and Fellow of the Royal College of Physicians of Edinburgh.

I was recruited to join Duke University Medical School as Associate Professor of Psychiatry and Behavioral Science. Then I was seconded to Duke-NUS Medical School as inaugural faculty. I was granted Tenure in 2012.

I started the Neurocognitive Genomics Laboratory in Duke-NUS and subsequently the Brain-Computer Interface Laboratory. With co-investigators we have researched and published in cognitive disorders, attention disorders and autism. I maintain close ties with my lab in New Haven working on mouse models and published with them. In recent times and for the future I am championing Autistic Spectrum Disorders research in Singapore.

As part of my Duke-NUS appointment, I do clinical work (30% FTE) at Singapore General Hospital Department of Psychiatry where I started the Neuropsychiatry Subspecialty Clinic. Through seminars, team-based, bedside and clinic-based teaching, I am active in the education of Duke-NUS medical students, specialist trainees and peer specialists.

The Ministry of Health, Singapore, appointed me Deputy Chief Examiner for Psychiatry in 2014 when we set up the new psychiatry specialty examination jointly with the American Board of Medical Specialties.

At the Academy of Medicine Singapore I set up and was inaugural Chairman of the Section of Neuropsychiatry from 2017 till 2021.

Education

Doctor of Philosophy

Yale University, United States

Master of Psychological Medicine

University of New South Wales, Australia

Doctor of Medicine

Yale University, United States

Bachelor of Science with Hons

Northwestern University, United States

Details

Bio

Education

Doctor of Philosophy

Master of Psychological Medicine

Doctor of Medicine

Bachelor of Science with Hons

Academic Contribution(s)

Duke-NUS Pioneer Award

Duke-NUS Teaching Award

Membership

Chair, Section of Neuropsychiatry

Research Interests

Publications

A brain-computer interface based attention training program for treating attention deficit hyperactivity disorder.

Home-based brain-computer interface attention training program for attention deficit hyperactivity disorder: a feasibility trial.

Brain-computer interface based attention and social cognition training programme for children with ASD and co-occurring ADHD: A feasibility trial.

A pilot randomized controlled trial using EEG-based brain-computer interface training for a Chinese-speaking group of healthy elderly.

Gene expression in the epileptic (EL) mouse hippocampus.

Network-Related Changes in Neurotransmitters and Seizure Propagation During Rodent Epileptogenesis.

A brain-computer interface based cognitive training system for healthy elderly: a randomized control pilot study for usability and preliminary efficacy.

Trait-like nocturnal sleep behavior identified by combining wearable, phone-use, and self-report data.

Downregulation of TOMM40 expression in the blood of Alzheimer disease subjects compared with matched controls.

Analysis of blood-based gene expression signature in first-episode psychosis.

Details

Bio

Education

Doctor of Philosophy

Master of Psychological Medicine

Doctor of Medicine

Bachelor of Science with Hons

Academic Contribution(s)

Duke-NUS Pioneer Award

Duke-NUS Teaching Award

Membership

Chair, Section of Neuropsychiatry

Research Interests

Publications

A brain-computer interface based attention training program for treating attention deficit hyperactivity disorder.

Home-based brain-computer interface attention training program for attention deficit hyperactivity disorder: a feasibility trial.

Brain-computer interface based attention and social cognition training programme for children with ASD and co-occurring ADHD: A feasibility trial.

A pilot randomized controlled trial using EEG-based brain-computer interface training for a Chinese-speaking group of healthy elderly.

Gene expression in the epileptic (EL) mouse hippocampus.

Network-Related Changes in Neurotransmitters and Seizure Propagation During Rodent Epileptogenesis.

A brain-computer interface based cognitive training system for healthy elderly: a randomized control pilot study for usability and preliminary efficacy.

Trait-like nocturnal sleep behavior identified by combining wearable, phone-use, and self-report data.

Downregulation of TOMM40 expression in the blood of Alzheimer disease subjects compared with matched controls.

Analysis of blood-based gene expression signature in first-episode psychosis.

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