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Spinning out a cancer immunotherapy startup - The story of PairX Bio

An event recording is available below. 

PairX Event

Singapore has a thriving ecosystem of scientists, investors and funding agencies committed to promoting Bio-entrepreneurship in the life science sector. One such exciting space is the SingHealth Duke-NUS Academic Medical Centre (AMC), where innovation and entrepreneurship comes alive.

In this webinar, we will feature the story of PairX Bio ("PairX"), a new Singapore-based Biotech Company in cancer immunotherapy and latest spin-off from Duke-NUS AMC. The panel featuring Dr Raymond Lee, Scientific Co-founder of PairX; Mr XQ Lin, an investor in PairX; and Ms Cheryl McCaffrey, Director of Duke-NUS' CTeD, will share their insights on the opportunities and challenges of starting a biotech company.

We invite you to join us in the first Duke-NUS Bio-entrepreneurship event powered by BCS, and learn more about exciting innovations in Singapore’s Biotech ecosystem.

Program:
Panel discussion
Q&A session

Speaker's Profile:

Raymond Lee

Raymond did his PhD and subsequent Post-doc training in developmental biology and cell signalling. Through lineage tracing experiments he showed that fin rays were not derived from neural crest cells in the trunk challenging long-held ideas about the fate of these cells. Subsequently in David Epstein’s laboratory at Duke NUS Medical School, he worked on aberrant splicing during cancer formation. A casual conversation with David Epstein over whether tumor associated splice variants might be immunogenic or not, led to the development of screens to test this hypothesis. The start-up PairX Bio uses this technology to develop next generation cancer immunotherapies targeting shared antigens from aberrantly splice proteins.

XQ Lin

XQ Lin is a seasoned global life sciences business leader and entrepreneur. Financially independent since age 13, XQ is a Wharton graduate, lived and worked in the US, China and Singapore and has extensive operating and investment experience in Europe. At a young age, XQ transformed Esco into a global life science and medical technologies group, growing shareholder value 25% CAGR over 20 years (since 2000). Today, Esco is Singapore’s most global life sciences company, with operations (including R&D and manufacturing) across the US, Europe and China, and over 1400 employees.
XQ founded Esco Ventures in 2014, which has invested in several startups with a portfolio IRR ~45% to date and Esco Ventures X in 2018- Asia’s springboard for biotech startups operating across Singapore and Boston. Esco Ventures X launched the Morphosis venture fellowship in 2018 for talent development, and the PLATINUM program in 2020 (pre seed grant funding to academic labs). He is the Founding CEO of Carmine Therapeutics which is pioneering a new class of redosable gene therapies based on red blood cell extracellular vesicles. Carmine recently inked a USD900M+ biobucks deal with Takeda. He is an investor in PairX Bio, a cancer immunotherapy spinout from Duke-NUS which was incubated at Esco Ventures X.

Deputy Director CTeD, Cheryl McCaffery

Ms. McCaffery is Director of the Centre for Technology and Development (CTeD), where she oversees a team whose role it is to identify, direct the further development of, and determine and execute commercialisation strategies for inventions arising in the School. Prior to moving to Duke-NUS in 2014, she was Deputy Director of A*STAR’s Industry Development Group in the Biomedical Sciences Institutes for seven years. Ms. McCaffery has had extensive experience in research management, strategic I.P. management, collaborations and alliance management, start-up formation, strategic planning, business development and corporate governance, and has negotiated numerous large research/licensing deals, and been involved in establishing and licensing sixteen start-up companies.
Ms. McCaffery originally trained as a biochemist; she holds a BSc (Hons1) degree from the University of N.S.W. and spent 10 years doing bench research in neuroscience and cancer research before pursuing a MBA at Melbourne Business School and moving into the business side of biomedical science. She is also a registered Patent Attorney, a Certified Licensing Professional and a Graduate of the Australian Institute of Company Directors.  

Event Recording




Organized by:

cted transparent    duke-nus-transparent    Joint Centre for Technology and Development-vertical

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Biotech Connection Singapore

 


Date and Time


09 Sep 2020 @ 11:00 - 09 Sep 2020 @ 12:00

Registration


Click Here to Register

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