Systems Metabolomics Centre (SysMeC)

Systems Metabolomics Centre (SysMeC)

Overview

The Systems Metabolomics Centre (SysMeC) is a joint centre between NUS School of Medicine and Duke-NUS Medical School, officially launched on 27 February 2025 during the 13th International Singapore Lipid Symposium (ISLS 13). SysMeC brings together the complementary strengths of both institutions to advance the field of metabolomics through cutting-edge technology, cross-disciplinary collaboration, and translational research.

Our Vision

SysMeC aims to serve as a blueprint for a centralised resource in multi-omic analysis and systems biology - on par with the world's leading universities and research institutions.

We pursue this vision by:

Harmonising mass spectrometry infrastructure and expertise across NUS and Duke-NUS to maximise efficiency and scientific impact.
Supporting both basic and clinical research through robust, high-quality metabolomic platforms that are accessible and scalable.
Fostering collaboration with clinical, academic, and industry partners to advance translational research and real-world applications.
Driving innovation through the development of new analytical platforms, advanced assays, and cutting edge data science capabilities.

By unifying capabilities and engaging across the national and international partners, SysMeC aims to deliver a world-class systems biology platform - positioning ourselves at the forefront of global metabolomics research.

Core Capabilities

SysMeC’s integrated infrastructure and expertise enable:

State-of-the-art instrumentation for lipidomics and polar metabolite analysis.
Analytical and quantitative assay development across metabolic pathways.
Multi-omic integration and data analytics, supported by a dedicated data science team.
Metabolite-protein interaction profiling and microbiome-metabolome exploration.

Facilities

NUS SLING (Singapore Lipidomics Incubator)

Located within NUS, SLING operates 18 LC-MS platforms supported by robotics, automated sample prep, and advanced storage infrastructure. It plays a key role in ISO accreditation and industry engagement.

Duke-NUS/SingHealth Mass Spectrometry Core

This facility houses 6 platforms and is currently undergoing upgrades to maintain global competitiveness. It includes collaborative capabilities with SingHealth Research Institutes.

Contact Us

Duke-NUS Medical School

Yibin Wang, Ph.D. | Professor, Programme Director, Cardiovascular and Metabolic Disorders Programme
Email: yibinwang@duke-nus.edu.sg

Federico Torta, Ph.D. | Assistant Professor, Cardiovascular and Metabolic Disorders Programme
Email: bchfdtt@duke-nus.edu.sg

NUS School of Medicine

Roger Foo, M.D. | Professor, Senior Vice-Dean (Research), Yong Loo Lin School of Medicine
Email: mdcrfsy@nus.edu.sg

Choi Hyung Won, Ph.D. | Associate Professor, Yong Loo Lin School of Medicine
Email: mdchwc@nus.edu.sg