Wang Jie Jin



Contact: 66017231

Wang Jie Jin is a professor of epidemiology and the deputy director of the Centre for Clinician-Scientist Development (CCSD) at the Duke-NUS Medical School. Prior to this position she was an associate professor (2007-2011) and professor (2012-2018) at the University of Sydney, a Senior Research Fellow of National Health and Medical Research Council (NHMRC), Australia (2005-2015 inclusive) and an associate professor at the University of Melbourne (2006-2013). She obtained a Masters and a PhD degrees in epidemiology from University of Sydney and a Masters degree in Applied Statistics from Macquarie University, Sydney.

Jie Jin has conducted epidemiological research in visual impairment and the two common causes of visual impairment in older people: age-related macular degeneration (AMD) and age-related cataract. She has been a key investigator of the Blue Mountains Eye Study, a population-based cohort study over 15 years. She expanded many projects using this cohort in collaboration with international researchers in a number of consortia. She led a clinic-based cohort study of 2000 cataract surgical patients to clarify a long-term debate over the possible adverse effect of cataract surgery on AMD risk. Jie Jin and her team documented the associations of visual impairment with poor survival, and correction of visual impairment with better survival among older people in two independent cohorts. She leads investigation of joint contribution of modifiable factors and genetic susceptibility to the risk of AMD and age-related cataract.

Jie Jin was the primary supervisor of 9 PhD and 4 Masters candidates enrolled in the University of Sydney or University of Melbourne, and all 13 candidates had their degrees awarded. She was an associate supervisor of additional 13 PhD and 2 Masters candidates with degrees awarded. Jie Jin is a co-author of 616 original research reports, 19 reviews and 6 book chapters. Jie Jin was a member of Australian NHMRC Project Grant Review Panels from 2011 to 2014 consecutively. She served as the Editor-in-Chief of Ophthalmic Epidemiology from 2011 to 2016.

Jie Jin’s position in Duke-NUS is to provide grantsmanship guidance and support to SGH clinicians to win national funding for their pursuing clinician-scientist careers. Over 3 years since her joining Duke-NUS (2017 to 2019 inclusive), Jie Jin and the CCSD team, together with Duke-NUS senior researchers as workshop mentors, supervised 17 CSA-INV applicants (15 first CSA applicants) and 16 TA applicants within the grantsmanship program, ACE-in-Grants. Of those, 12 CSA applicants, 9 TA applicants were successfully awarded, and 7 submitted in November 2019 with outcome pending.  

Research Interests

  1. Epidemiology of age-related macular degeneration
  2. Epidemiology of age-related cataract
  3. Epidemiology of visual impairment in older population
  4. Retinal vascular parameters as small vessel disease indicators for cerebrovascular and cardiovascular conditions

Selected 10 Published Research Articles

  1. Wang JJ, Rochtchina E, Liew G, Tan AG, Wong TY, Leeder SR, Smith W, Shankar A, Mitchell P. The long-term relationship between retinal arteriolar narrowing, blood pressure and incident severe hypertension. American Journal of Epidemiology 168:80-88, 2008
  2. Wang JJ, Rochtchina E, Smith W, Klein R, Klein BEK, Joshi T, Sivakumaran TA, Iyengar S, Mitchell P. Combined effects of Complement Factor H genotypes, fish consumption, and inflammatory markers on long-term risk of age-related macular degeneration in a cohort. American Journal of Epidemiology 169:633-641, 2009
  3. Wang JJ*, Baker ML*, Hand PJ, Hankey GJ, Lindley RI, Rochtchina E, Wong TY, Liew G, Mitchell P. The Multi-Centre Retinal Stroke Study Group. TIA and acute ischemic stroke: Associations with retinal microvascular signs. Stroke 42:404-408, 2011
  4. Wang JJ, Fong CS, Rochtchina E, Cugati S, de Loryn T, Kaushik S, Tan JSL, Arnold J, Smith W, Mitchell P. Risk of Age-related Macular Degeneration 3 Years after Cataract Surgery: Paired Eye Comparisons. Ophthalmology 119:2298-2303, 2012
  5. Fong CS, Mitchell P, Rochtchina E, Teber ET, Hong T, Wang JJ. Correction of visual impairment by cataract surgery and improved survival in older persons: The Blue Mountains Eye Cohort. Ophthalmology 120:1720-1727, 2013   
  6. Wang JJ, Buitendijk GHS, Rochtchina E, Lee KE, Klein BEK, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, et al. Genetic susceptibility, dietary antioxidants and long-term risk of age-related macular degeneration in two populations. Ophthalmology 121:667-675, 2014
  7. Joachim N, Mitchell P, Burlutsky G, Kifley A, Wang JJ. The Incidence and Progression of   Age-Related Macular Degeneration over 15 Years: The Blue Mountains Eye Study. Ophthalmology 122(12):2482-2489, 2015
  8. Wang JJ, Fong CS, Burlutsky G, Cugati S, Tan AG, Rochtchina E, Arnold J, Smith W, Mitchell P. Risk of Age-related Macular Degeneration 4 to 5 Years after Cataract Surgery. Ophthalmology 123(8):1829-2830, 2016
  9. Joachim N*, Kifley A*, Colijn JM, Lee KE, Buitendijk GHS, Klein BEK, Myers C, Meuer SM, Tan AG, …, Wang JJ*. Joint Contribution of Genetic Susceptibility and Modifiable Factors to the Progression of Age-related Macular Degeneration (AMD) over 10 Years: The Three Continent AMD Consortium Report. Ophthalmology Retina 2:684-693, 2018
  10. Tan AG, Kifley A, Flood VM, Holliday EG, Scott RJ, Cumming RG, Mitchell P, Wang JJ. Evaluating the associations between obesity and age-related cataract: A Mendelian Randomization Study. American Journal of Clinical Nutrition 110(4):969-976, 2019