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SingHealth Duke-NUS Academic Medical Centre leads S$10m national effort to tackle muscle-loss in ageing Singapore

Supported by the National Research Foundation, Singapore under the National Medical Research Council (NMRC) Research, Innovation and Enterprise 2025 Open Fund - Large Collaborative Grant (OF-LCG) programme and administered by the Singapore Ministry of Health through the NMRC Office, MOH Holdings Pte Ltd, the project—named MAGNET (Mechanistic Investigation and Clinical Innovation for Sarcopenia Diagnosis and Therapy)—will position Singapore as a leader in sarcopenia research globally and is expected to bring critically needed innovations to how the condition is detected and treated, particularly among Asian patients.

Based on a study by the Asian Working Group for Sarcopenia[1], sarcopenia affects nearly one in three Singaporeans aged 60 and above, impacting mobility, independence and quality of life. It also affects younger adults with chronic diseases such as cancer and diabetes—one in 14 Singaporeans under 60 are estimated to have sarcopenia[2]. Sarcopenia has also been found to be an independent risk factor for poorer health-related outcomes[3], such as earlier cancer recurrences and increased hospital admissions, leading to increased healthcare burden[4]. Read more>>

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