When the SingHealth Duke-NUS Academic Medical Centre launched its first regional Asia Pacific Global Health Hackathon in January 2025, few could have predicted the scale of creativity that would emerge. From Malaysia to Indonesia, multidisciplinary teams of scientists, clinicians, engineers and entrepreneurs gathered to tackle one question: How can innovation strengthen health systems in a warming world? 

Nine months later, the winning teams - RodentWatch (Indonesia), MyHeartAir (Malaysia), and Lung Guardian (Thailand, Malaysia and Mongolia) returned to Singapore for a three-day Fellowship Visit hosted by the SingHealth Duke-NUS Global Health Institute (SDGHI). The visit, held from 13 to 15 October, marked the culmination of a 22-week incubation journey that paired the innovators with clinicians, entrepreneurs and industry mentors to refine their prototypes and pitches. 

“We didn’t want this hackathon to end with good ideas on paper. We wanted to see ideas evolve; tested, challenged, and built into solutions that can make an impact across ASEAN.” said Dr Jonas Karlstroem, Lead (Innovation), SingHealth Duke-NUS Global Health Institute.  


Rodent Watch: Predicting zoonotic outbreaks before they happen  

Emerging from North Sumatra’s flood-prone agricultural heartland, Rodent Watch tackles a neglected but growing public-health threat - leptospirosis, a rodent-borne disease that disproportionately affects farmers. 

The team’s predictive AI platform integrates rainfall, temperature and soil-moisture data with epidemiological inputs to generate real-time risk maps, identifying potential outbreak zones before cases surge. During the fellowship, the team shared how community engagement remains central to their vision. 

“We want farmers and residents to be part of the solution by uploading photos or sightings of rodents through a mobile app,” they explained. “It’s about transforming surveillance into citizen science.” 

Rodent Watch’s pitch to the United Nations Development Programme (UNDP) has already drawn international attention, aligning with global calls for climate-resilient, One Health systems that link environmental, animal and human health data. Their next step: pilot partnerships with local governments and pest-control companies to operationalise their early-warning model and eventually expand to other climate-sensitive diseases such as dengue or hantavirus. 



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Lung Guardian: Turning a child’s toy into a lifesaving companion

Lung Guardian approaches health innovation through a deeply human lens. The team has built a smart keychain device shaped like Labubu – a popular character created by artist Kasing Lung - that monitors air quality and provides real-time respiratory risk alerts. 

Powered by IoT sensors and AI analytics, the keychain syncs with a mobile app to help users track exposure to particulate matter (PM 2.5), offering tailored prompts when air quality deteriorates. 

“We wanted something children would actually carry - a friendly guardian that protects their lungs,” said co-founder Chitsanupong Ratarat (Will). “Parents are our first users, but the vision is to make air-health awareness part of everyday life.” 

Using the grant received for the fellowship, the team is refining its prototype for user testing and exploring collaborations for pilot studies with hospitals and family-health organisations. With interest from angel investors and multinational organisations, future phases of Lung Guardian will include AI-driven predictive modelling to forecast asthma attacks and integration with telehealth or occupational-health platforms. Beyond function, Lung Guardian is also exploring emotional design — developing multiple Labubu characters to encourage children’s attachment and sustained use. 

 

 

 

 

 

 

 

MyHeartAir: The future of cardiovascular coaching

Cardiovascular disease remains Asia-Pacific’s leading cause of death - accounting for nearly one-third of all mortality. Enter MyHeartAir, a Malaysian digital-health startup founded by cardiologists, bioinformaticians and entrepreneurs.  

The platform uses AI-powered predictive analytics to link air quality, physiological data and behaviour patterns, providing personalised coaching for users at risk of heart disease or recovering from cardiac events. 

“Conventional heart-risk algorithms are based on Western populations,” explained lead cardiologist Dr Sazzli Kassim “We built a model calibrated for Asian data - and then layered on air-pollution exposure, which most systems ignore.” 

MyHeartAir has since been incorporated in Malaysia, with angel investment secured and a pilot in partnership with the Ministry of Health planned for early 2026. The startup is also working with insurers and telemedicine providers on subscription-based access, making preventive heart care both accessible and scalable. Its scientific rigour is already recognised: the team’s AI work has been featured in The Lancet, Scientific Reports, and was honoured at the World Summit on the Information Society (WSIS) 2025 in Geneva. 

 

 

 

 

 

 

 

 

 

From mentorship to market: Building ASEAN’s innovation ecosystem 

Throughout the 22-week incubation, each team worked closely with three mentors — clinician-scientists, entrepreneurs and investors — to refine both their science and their story. They also pitched to venture-capital networks and ecosystem partners such as SGInnovate, Microsoft, UNDP, Endeavor Catalyst and Blu Maiden Capital, gaining real-world feedback on business viability and impact scaling. 

“We learnt that innovation is not just about technology — it’s about clarity,” said one participant. “The mentorship helped us translate complex science into language that funders and users understand.” 

As profiled by GovInsider in its recent feature, “The case for academic incubators to drive ASEAN’s healthcare breakthroughs”, the Hackathon-to-Fellowship model is emerging as a blueprint for academic innovation in the region — bridging research, entrepreneurship and public good. “Our academic incubator turns questions into prototypes and prototypes into possibilities.” said Dr Daniel Mahadzir, Innovation Research Fellow at the SingHealth Duke-NUS Global Health Institute, who is the primary architect behind the fellowship. 

 

Looking ahead 

From rodent surveillance in flood-prone fields to portable devices safeguarding lungs and hearts in smog-filled cities, these innovators share a single mission: to make data-driven health solutions accessible where they’re needed most. 

“This is what regional innovation should look like — locally rooted, globally relevant,” said Prof London Lucien Ooi, SDGHI Director. “By investing in young scientists and clinicians across ASEAN, we’re not just building products, we are building resilience.” 

As the teams prepare for their next milestones: pilot deployments, regulatory consultations and funding rounds,their journey reflects a powerful truth: that the most impactful health technologies often begin not in boardrooms, but in small teams driven by purpose, empathy and a shared vision for a healthier planet. 


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