Chetna Malhotra, Assistant Professor, Lien Centre for Palliative Care, Duke-NUS Medical School, Singapore
David Sim Kheng Leng, Than Aung, Yeo Khung Keong, Chetna Malhotra, Semra Özdemir, Irene Teo Eng Ai, Nivedita Nadkarni
Chronic heart failure (CHF) is one of the leading causes of death in Singapore. Although it is well established that CHF patients in Singapore are less likely to be referred to palliative care services than cancer
patients, little data is available on end of life experience of advanced CHF patients in Singapore, including the inter-relationships between patient decision-making, quality of life trajectories, and health and cost
The objective of this cohort study is to better understand the relationship between patient preferences, health care access, utilization, costs, and quality of life, and to identify strategies to improve the EOL
experience for these patients.
Prospective study of patients with advanced heart failure (New York Heart Association class III and IV). 250 patients and their primary informal caregivers are followed every 4 months for a period of two years or till
they die, whichever is earlier. Treating physicians of the patients are invited to take part in the study.
National Heart Centre Singapore
Singapore General Hospital
The results of the cohort study with patients with advanced CHF will be useful to better understand the role that patient, family, and health system characteristic play in determining health outcomes, utilization and
costs of care and for identifying inappropriate use of services, quality improvement initiatives, resource allocation, and budgeting.
Malhotra C, Foo R, Singh R, Ozdemir S, Teo I, Sim D, Jaufeerally FR, Aung T, Yeo KK, Nadkarni N, Finkelstein EA. BMJ Open.2018;8(9):e022248.
Ozdemir S, Teo I, Bundoc FC, Malhotra C, Yeo KK, Sim DKL, Finkelstein EA. Patient Education and Counseling.2020; S0738-3991(20)30464-X.
Malhotra, C., Bundoc, F., Ang, F., Ozdemir, S., Teo, I., Sim, D., Jaufeerally, F. R., Aung, T., & Finkelstein, E. (2021). Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 30(5), 1379–1387. https://doi.org/10.1007/s11136-020-02736-7
Project Start Date:
1 October 2016