Research

Quality of Care for Patients with Advanced Illness (QCPAI) 2.0

Quality of Care for Patients with Advanced Illness (QCPAI) 2.0

This study builds on prior work on the development, validation, and elicitation of QCPAI among patients with advanced cancer.

The QCPAI 2.0 aims to expand the validity of the QCPAI instrument across multiple advanced disease populations (cancer, heart, lung, and kidney) and healthcare settings (outpatient, inpatient, and hospice) in Singapore. It will survey 500 patients and 100 family caregivers to rigorously evaluate the instrument's measurement properties, language version equivalence, and patient-proxy response concordance. Concurrently, a Discrete Choice Experiment (DCE) survey will be conducted to establish a robust, patient-preference-weighted scoring algorithm.

The expected outcome is a standardized, value-based index that enables healthcare organizations and policymakers to objectively evaluate, benchmark, and optimize person-centric end-of-life care delivery.

Principal Investigator

Assistant Professor Mihir Gandhi, Lien Centre for Palliative Care, Duke-NUS Medical School

Study Team

Duke-NUS Medical School

  • Prof. Eric Andrew Finkelstein
  • Prof. Yin Bun Cheung
  • A/Prof. Juan Marcos Gonzalez Sepulveda
  • Dr. Felicia Ang Jia Ler
  • Dr. Tan See Mieng

National University Hospital

  • Dr. Lim Shir Lynn (Site-PI)
  • Dr. Chan Noreen
  • Dr. Ng Perryn
  • Dr. Sia Charmaine

National Cancer Centre Singapore

  • Dr. Neo Hui Shan Shirlyn (Site-PI)
  • Dr. Alethea Yee Chung Pheng
  • Dr. Wong Si Min Jolene
  • Dr. Ravindra Kanesvaran
  • Dr. Irene Teo

National Heart Centre Singapore

  • Dr. Tan Ru San (Site-PI)
  • Dr. Sim Kheng Leng David
  • Dr. Teo Loon Yee Louis
  • Dr. Wong Ningyan

Singapore General Hospital

  • Dr. Chew Si Yuan (Site-PI)
  • Dr. Tiew Pei Yee
  • Dr. Sheryl Gan Shien Wen
  • Dr. Choong Hui Ling
  • Dr. Koh Siyue Mariko
  • Dr. Jason Choo Chon Jun
  • Dr. Chai Hui Zhong
  • Dr. Kam Li Wei Michelle
  • Dr. Lee Cheah Hooi Ken
  • Dr. Leow Leong Chai
  • Dr. Low Su Ying
  • Dr. Ong Thun How
  • Dr. Tan Yi Hern
  • Dr. Toh Weiquan Timothy
  • Dr. Kwek Jia Liang
  • Dr. Woong Liling Natalie

Assisi Hospice

  • Dr. Tan Su-Yen (Site-PI)

HCA Hospice

  • Dr. Poh Heng Chong (Site-PI)

Presentations

Poster presentation: Development of A Patient-Preference-Weighted Scoring Algorithm For The Quality of Care For Patients With Advanced Illness (QCPAI) In A Multi-Ethnic Asian Setting, ISPOR 2026, 17–20 May 2026, Philadelphia, USA

Any Other Information

The study is funded by the National Medical Research Council, Singapore.

Contact Person

Assistant Professor Mihir Gandhi: mihir.gandhi@duke-nus.edu.sg

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