Medicine

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Medicine

Goh Boon Bee George

Clinical Associate Professor, SingHealth Duke-NUS Medicine Academic Clinical Programme

gmsgohbb@duke-nus.edu.sg

About

Academic Contributions

Professional

Publications

Bio

Dr. George Goh is a Senior Consultant Gastroenterologist and Hepatologist at the Singapore General Hospital. After Gastroenterology specialist training at Singapore General Hospital, he underwent further advanced subspecialty training in Hepatology at the Cleveland Clinic (USA), with a research focus on non-alcoholic fatty liver disease (NAFLD). He returned to establish a dedicated Metabolic Liver Clinic with multi-disciplinary involvement that helps to identify, prognosticate and manage patients with severe NAFLD. In addition, he remains actively involved in research and is the local Principal Investigator of several ongoing international NAFLD trials. He has published in the fields of NAFLD, liver cirrhosis, hepatocellular carcinoma and organ transplantation, and has been an invited faculty at both local and international conferences.

Dr. Goh is an appointed Clinical Associate Professor at Duke-NUS Medical School and Clinical Lecturer at Yong Loo Lin School of Medicine, National University of Singapore. He is the current Chairman of the National Foundation of Digestive Disease (NFDD), which aims to increase awareness of such diseases among the general public.

Education

Member, Royal Coll of Physicians

Royal College of Physicians, UK, United Kingdom

Master of Medicine

National University of Singapore, Singapore

Bachelor of Medicine, Bachelor of Surgery

University of London, United Kingdom

Academic Contribution(s)

Singapore Health Quality Service Award - Gold Award

2017

SingHealth Publish Award

2016

AASLD Poster of Distinction

2016

Service with a Heard Award

2015

SingHealth Publish Award - Outstanding

2015

Professional Appointment(s)

Clinical Assistant Professor

Yong Loo Lin (YLL) School of Medicine, National University of Singapore, Currently Active

Senior Consultant Gastroenterology ＆ Hepatology

Singapore General Hospital, Currently Active

Clinical Teacher

Lee Kong Chian (LKC) School of Medicine, Nanyang Technological University, Currently Active

Chairperson, Executive Committee

National Foundation of Digestive Diseases, Singapore, Currently Active

Membership

Fellow

Academy of Medicine, Singapore, Currently Active

Fellow

American Association for the Study of Liver Disease (AASLD), -

Publications

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease.

Hepatology international – Eslam Mohammed; Fan Jian-Gao; Yu Ming-Lung; Wong Vincent Wai-Sun; Cua Ian Homer; Liu Chun-Jen; Tanwandee Tawesak; Gani Rino; Seto Wai-Kay; Alam Shahinul; Young Dan Yock; Hamid Saeed; Zheng Ming-Hua; Kawaguchi Takumi; Chan Wah-Kheong; Payawal Diana; Tan Soek-Siam; Goh George Boon-Bee; Strasser Simone I; Viet Hang Dao; Kao Jia-Horng; Kim Won; Kim Seung Up; Keating Shelley E; Yilmaz Yusuf; Kamani Lubna; Wang Chia-Chi; Fouad Yasser; Abbas Zaigham; Treeprasertsuk Sombat; Thanapirom Kessarin; Al Mahtab Mamun; Lkhagvaa Undram; Baatarkhuu Oidov; Choudhury Ashok Kumar; Stedman Catherine A M; Chowdhury Abhijit; Dokmeci A Kadir; Wang Fu-Sheng; Lin Han-Chieh; Huang Jee-Fu; Howell Jess; Jia Jidong; Alboraie Mohamed; Roberts Stuart K; Yoneda Masato; Ghazinian Hasmik; Mirijanyan Aram; Nan Yuemin; Lesmana Cosmas Rinaldi Adithya; Adams Leon A; Shiha Gamal; Kumar Manoj; Örmeci Necati; Wei Lai; Lau George; Omata Masao; Sarin Shiv K; George Jacob (2025)

19 (2); 261-301

Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the Phase 2b TANDEM study.

Hepatology – Quentin M Anstee, Kathryn J Lucas, Sven Francque, Manal F Abdelmalek, Arun J Sanyal, Vlad Ratziu, Adrian C Gadano, Mary Rinella, Michael Charlton, Rohit Loomba, Edward Mena, Jörn M Schattenberg, Mazen Noureddin, Donald Lazas, George BB Goh, Shiv Kumar Sarin, Yusuf Yilmaz, Miljen Martic, Rowan Stringer, Jossy Kochuparampil, Li Chen, Gerardo Rodriguez-Araujo, Elaine Chng, Nikolai V Naoumov, Clifford Brass, Marcos Pedrosa. (2023)

78 1223-1239

The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?

J Hepatol. – Jeffrey V Lazarus, Henry E Mark, Marcela Villota-Rivas, Adam Palayew, Patrizia Carrieri, Massimo Colombo, Mattias Ekstedt, Gamal Esmat , Jacob George , Giulio Marchesini, Katja Novak, Ponsiano Ocama, Vlad Ratziu, Homie Razavi, Manuel Romero-Gómez, Marcelo Silva , C Wendy Spearman, Frank Tacke, Emmanuel A Tsochatzis, Yusuf Yilmaz, Zobair M Younossi, Vincent W-S Wong, Shira Zelber-Sagi, Helena Cortez-Pinto, Quentin M Anstee, NAFLD policy review collaborators. (2021)

Vitamin (B12 and Folate) dietary supplementation prevents and decreases inflammation and fibrosis in non-alcoholic steatohepatitis (NASH).

Jou Hep – Madhulika Tripathi, Brijesh Kumar Singh, Jin Zhou, Keziah Tikno, Anissa Widjaja, Reddemma Sandireddy, Siti Aishah Binte Abdul Ghani, George Goh Boon Bee, Kiraely Adam Wong, Ho Jia Pei, Shamini Guna Shekeran, Rohit Anthony Sinha, Manvendra Kumar Singh, Stuart Cook, Chris Newgard, Ruiping Xiao, Xiuqing Zhang, Ayako Suzuki, Pierce K. H. Chow, Paul Michael Yen. (2022)

Advancing the global public health agenda for NAFLD: a consensus statement.

Nat Rev Gastroenterol Hepatol. – Lazarus JV, Mark HE, Anstee QM, Arab JP, Batterham RL, Castera L, Cortez-Pinto H, Crespo J, Cusi K, Dirac MA, Francque S, George J, Hagström H, Huang TT, Ismail MH, Kautz A, Sarin SK, Loomba R, Miller V, Newsome PN, Ninburg M, Ocama P, Ratziu V, Rinella M, Romero D, Romero-Gómez M, Schattenberg JM, Tsochatzis EA, Valenti L, Wong VW, Yilmaz Y, Younossi ZM, Zelber-Sagi S; NAFLD Consensus Consortium. (2022)

Current modalities of fibrosis assessment in Non-Alcoholic Fatty Liver Disease.

Journal of Clinical and Translational Hepatology – Mark C Cheah, Arthur J McCullough, Goh BB. (2017)

5 1-11

The Natural History of NAFLD.

Dig Dis Sci – GBB Goh, AJ McCullough. (2016)

61 1226-1233

The increasing clinical burden of NAFLD in Asia.

The lancet. Gastroenterology & hepatology – De Roza Marianne Anastasia; Goh George Boon-Bee (2019)

4 (5); 333-334

Considerations for bariatric surgery in patients with cirrhosis.

World Journal Gastroenterology – George Boon-Bee Goh, Phil Schauer, Arthur J McCullough. (2018)

3112-3119

Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial.

Nature medicine – Sanyal Arun J; Lopez Patricia; Lawitz Eric J; Lucas Kathryn J; Loeffler Juergen; Kim Won; Goh George B B; Huang Jee-Fu; Serra Carla; Andreone Pietro; Chen Yi-Cheng; Hsia Stanley H; Ratziu Vlad; Aizenberg Diego; Tobita Hiroshi; Sheikh Aasim M; Vierling John M; Kim Yoon Jun; Hyogo Hideyuki; Tai Dean; Goodman Zachary; Schaefer Felicity; Carbarns Ian R I; Lamle Sophie; Martic Miljen; Naoumov Nikolai V; Brass Clifford A (2023)

29 (2); 392-400

Unhealthy lifestyle habits and physical inactivity among patients with nonalcoholic fatty liver disease in the multicenter CAP-Asia study.

Liver Int. – Xinrong Zhang, George Boon-Bee Goh, Wah-Kheong Chan, Grace Lai-Hung Wong, Jiangao Fan, Wai-Kay Seto, Yi-Hsiang Huang, Han-Chieh Lin, I-Cheng Lee, Hye Won Lee, Seung Up Kim, Wan Cheng Chow, Vincent Wai-Sun Wong. (2020)

40 2719-2731

Optimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients With Advanced Fibrosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association – Chan Wah-Kheong; Treeprasertsuk Sombat; Goh George Boon-Bee; Fan Jian-Gao; Song Myeong Jun; Charatcharoenwitthaya Phunchai; Duseja Ajay; Dan Yock-Young; Imajo Kento; Nakajima Atsushi; Ho Khek-Yu; Goh Khean-Lee; Wong Vincent Wai-Sun (2019)

17 (12); 2570-2580.e37

Coffee, alcohol and other beverages in relation to cirrhosis mortality: the Singapore Chinese Health Study.

Hepatology (Baltimore, Md.) – Goh George Boon-Bee; Chow Wan-Cheng; Wang Renwei; Yuan Jian-Min; Koh Woon-Puay (2014)

60 (2); 661-9

qFIBS: An Automated Technique for Quantitative Evaluation of Fibrosis, Inflammation, Ballooning, and Steatosis in Patients With Nonalcoholic Steatohepatitis.

Hepatology (Baltimore, Md.) – Liu Feng; Goh George Boon-Bee; Tiniakos Dina; Wee Aileen; Leow Wei-Qiang; Zhao Jing-Min; Rao Hui-Ying; Wang Xiao-Xiao; Wang Qin; Wan Wei-Keat; Lim Kiat-Hon; Romero-Gomez Manuel; Petta Salvatore; Bugianesi Elisabetta; Tan Chee-Kiat; Harrison Stephen A; Anstee Quentin M; Chang Pik-Eu Jason; Wei Lai (2020)

71 (6); 1953-1966

Changing epidemiology of hepatocellular carcinoma in Asia.

Best Pract Res Clin Gastroenterol. – George Boon Bee GOH, Pik Eu CHANG, Chee Kiat TAN. (2015)

29 919-928

Association between diabetes mellitus and cirrhosis mortality: the Singapore Chinese Health Study.

Liver international : official journal of the International Association for the Study of the Liver – Goh George Boon-Bee; Pan An; Chow Wan-Cheng; Yuan Jian-Min; Koh Woon-Puay (2017)

37 (2); 251-258

Modeling NAFLD Disease Burden in Hong Kong, Singapore, South Korea, and Taiwan – 2019-2030.

Alimentary Pharmacology & Therapeutics – Estes, Chris; Chan, Henry; Chien, Rong-Nan; Chuang, Wan-Long; Goh , George Boon Bee; Fung, James; Hu, Tsung-Hui; Huang, Jee-Fu; Jang, Byoung Kuk; Jun, Dae Won; KAO, JIA-HORNG; Lee, Jin-Woo ; Lin, Han-Chieh; Razavi-Shearer, Katie; Seto, Wai-Kay; Wong, Grace; Wong, Vincent; Razavi, Homie. (2020)

51 801-811

Clinical Spectrum of Non-Alcoholic Fatty Liver Disease in patients with Diabetes Mellitus – Cross-sectional Study.

PLoS One. – Kaina Chen, Wei Kwan Sng, JHM Quah, Jin Liu, Bee Yen Chong, Hwee Khim Lee, Xue Fei Wang, Ngiap Chuan Tan, J. Chang, Hong Chang Tan, Yong Mong Bee and George Boon-Bee Goh. (2020)

Perceptions of Non Alcoholic Fatty Liver Disease – An Asian Community Based Study.

Gastroenterology Reports – George BB Goh, Clarence Kwan, Sze Ying Lim, Nanda KK Venkatanarasimha, Rafidah Abu Bakar, Thinesh L Krishnamoorthy, Hang Hock Shim, Kiang Hiong Tay, Wan Cheng Chow. (2016)

4 (2); 131-135

Deciphering the epidemiology of hepatocellular carcinoma through the passage of time; a study of 1401 patients across three decades.

Hepatology Communications – George Boon-Bee Goh, James Weiquan Li, Pik-Eu Chang, Clement Yihao Lin, Khuan-Yew Chow, Chee-Kiat Tan. (2017)

1 564-571

Medicine

Bio

Education

Member, Royal Coll of Physicians

Master of Medicine

Bachelor of Medicine, Bachelor of Surgery

Academic Contribution(s)

Singapore Health Quality Service Award - Gold Award

SingHealth Publish Award

AASLD Poster of Distinction

Service with a Heard Award

SingHealth Publish Award - Outstanding

Professional Appointment(s)

Clinical Assistant Professor

Senior Consultant Gastroenterology ＆ Hepatology

Clinical Teacher

Chairperson, Executive Committee

Membership

Fellow

Fellow

Publications

The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease.

Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the Phase 2b TANDEM study.

The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?

Vitamin (B12 and Folate) dietary supplementation prevents and decreases inflammation and fibrosis in non-alcoholic steatohepatitis (NASH).

Advancing the global public health agenda for NAFLD: a consensus statement.

Current modalities of fibrosis assessment in Non-Alcoholic Fatty Liver Disease.

The Natural History of NAFLD.

The increasing clinical burden of NAFLD in Asia.

Considerations for bariatric surgery in patients with cirrhosis.

Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial.

Unhealthy lifestyle habits and physical inactivity among patients with nonalcoholic fatty liver disease in the multicenter CAP-Asia study.

Optimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients With Advanced Fibrosis.

Coffee, alcohol and other beverages in relation to cirrhosis mortality: the Singapore Chinese Health Study.

qFIBS: An Automated Technique for Quantitative Evaluation of Fibrosis, Inflammation, Ballooning, and Steatosis in Patients With Nonalcoholic Steatohepatitis.

Changing epidemiology of hepatocellular carcinoma in Asia.

Association between diabetes mellitus and cirrhosis mortality: the Singapore Chinese Health Study.

Modeling NAFLD Disease Burden in Hong Kong, Singapore, South Korea, and Taiwan – 2019-2030.

Clinical Spectrum of Non-Alcoholic Fatty Liver Disease in patients with Diabetes Mellitus – Cross-sectional Study.

Perceptions of Non Alcoholic Fatty Liver Disease – An Asian Community Based Study.

Deciphering the epidemiology of hepatocellular carcinoma through the passage of time; a study of 1401 patients across three decades.

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