Paediatrics

Gilead Sciences Research Scholars Program in Liver Disease – Asia.

Gilead Sciences Research,2021

Outstanding Early Career Investigator Team Presentation in Cancer

The New York Academy of Sciences,2017

Best of young SingHealth and Duke-NUS Scientists

SingHealth/Duke-NUS Medical School,2016

Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma.

Gut – Chew Valerie; Chen Jinmiao; Lee Deming; Loh Evelyn; Lee Joyce; Lim Kiat Hon; Weber Achim; Slankamenac Ksenija; Poon Ronnie T P; Yang Henry; Ooi London Lucien P J; Toh Han Chong; Heikenwalder Mathias; Ng Irene O L; Nardin Alessandra; Abastado Jean-Pierre (2012)

61 (3); 427-38

Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients.

Journal of hepatology – Chew Valerie; Tow Charlene; Teo Marissa; Wong Hing Lok; Chan Jasmine; Gehring Adam; Loh Marie; Bolze Alexandre; Quek Richard; Lee Victor K M; Lee Kang Hoe; Abastado Jean-Pierre; Toh Han Chong; Nardin Alessandra (2010)

52 (3); 370-9

Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients.

Journal of the National Cancer Institute – Chew Valerie; Tow Charlene; Huang Caleb; Bard-Chapeau Emilie; Copeland Neal G; Jenkins Nancy A; Weber Achim; Lim Kiat Hon; Toh Han Chong; Heikenwalder Mathias; Ng Irene Oi-Lin; Nardin Alessandra; Abastado Jean-Pierre (2012)

104 (23); 1796-807

Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma.

Gut – Garnelo Marta; Tan Alex; Her Zhisheng; Yeong Joe; Lim Chun Jye; Chen Jinmiao; Lim Kiat Hon; Weber Achim; Chow Pierce; Chung Alexander; Ooi London Lucien Pj; Toh Han Chong; Heikenwalder Mathias; Ng Irene O L; Nardin Alessandra; Chen Qingfeng; Abastado Jean-Pierre; Chew Valerie (2017)

66 (2); 342-351

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Nature genetics – Bard-Chapeau Emilie A; Nguyen Anh-Tuan; Rust Alistair G; Sayadi Ahmed; Lee Philip; Chua Belinda Q; New Lee-Sun; de Jong Johann; Ward Jerrold M; Chin Christopher Ky; Chew Valerie; Toh Han Chong; Abastado Jean-Pierre; Benoukraf Touati; Soong Richie; Bard Frederic A; Dupuy Adam J; Johnson Randy L; Radda George K; Chan Eric Cy; Wessels Lodewyk Fa; Adams David J; Jenkins Nancy A; Copeland Neal G (2014)

46 (1); 24-32

Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma.

Nature Communications – Phuong HD Nguyen, Siming Ma, Cheryl ZJ Phua, Neslihan A Kaya, Hannah LH Lai, Chun Jye Lim, Jia Qi Lim, Martin Wasser, Liyun Lai, Wai Leong Tam, Tony KH Lim, Wei Keat Wan, Tracy Loh, Wei Qiang Leow, Yin Huei Pang, Chung Yip Chan, Ser Yee Lee, Peng Chung Cheow, Han Chong Toh, Florent Ginhoux, Shridhar Iyer, Alfred WC Kow, Yock Young Dan, Alexander Chung, Brian KP Goh, Salvatore Albani, Pierce KH Chow, Weiwei Zhai, Valerie Chew. (2021)

11 (12);

Immune microenvironment in tumor progression: characteristics and challenges for therapy

Journal of Oncology – Chew V, Toh HC, Abastado JP. (2012)

2012 (2012);

Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses.

Proceedings of the National Academy of Sciences of the United States of America – Chew Valerie; Lai Liyun; Pan Lu; Lim Chun Jye; Li Juntao; Ong Raymond; Chua Camillus; Leong Jing Yao; Lim Kiat Hon; Toh Han Chong; Lee Ser Yee; Chan Chung Yip; Goh Brian K P; Chung Alexander; Chow Pierce K H; Albani Salvatore (2017)

114 (29); E5900-E5909

Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma.

Gut – Chew Valerie; Lee Yun Hua; Pan Lu; Nasir Nurul J M; Lim Chun Jye; Chua Camillus; Lai Liyun; Hazirah Sharifah Nur; Lim Tony Kiat Hon; Goh Brian K P; Chung Alexander; Lo Richard H G; Ng David; Filarca Rene L F; Albani Salvatore; Chow Pierce K H (2019)

68 (2); 335-346

Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma.

Gut – Lim Chun Jye; Lee Yun Hua; Pan Lu; Lai Liyun; Chua Camillus; Wasser Martin; Lim Tony Kiat Hon; Yeong Joe; Toh Han Chong; Lee Ser Yee; Chan Chung Yip; Goh Brian Kp; Chung Alexander; Heikenwälder Mathias; Ng Irene Ol; Chow Pierce; Albani Salvatore; Chew Valerie (2019)

68 (5); 916-927