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Phua Kong Boo

Clinical Professor


Education Qualifications: MBBS (Q'ld), M Med (Paeds), FAMS, FRACP, FRCPCH

Clinical Professor Phua is actively involved in clinical service, research and both undergraduate and postgraduate teaching and examinations. He was officially appointed by NUS as a clinical teacher in 1972.  He was the Paediatric ACP Education Vice Chairman from 2011 to 2018.  Following which he became the Advisor to Paediatric ACP.

He chaired KKH Pharmacy and Therapeutic Committee from 2001 to 2014 and acted as an advisor from 2014.  He is now co‐chairing the MAF plus. He is a medical advisor for Club Rainbow.  He also serves in the Research and Residential Home (Sunbeam Place) Subcommittees of Singapore Children Society.

Professional Appointments:

  • 1999 – 2001 Head, Department of Paediatrics, KKH
  • April 1985 Senior Consultant, Department of Paediatrics, SGH

Committee Memberships:

  • Life Member, Singapore Medical Association
  • Life Member, Singapore Paediatric Society
  • Fellow, Academy of Medicine
  • Fellow, Australasian College of Physicians
  • Fellow, Royal College of Physician and Child Health


  • 2005 EXSA Award (Gold)                                                                               
  • 2006 Courage Fund Award 
  • 2006 Ruth Wong Award                                                                                      
  • 2007 KKH CEO Heart Award                                                                                
  • 2008 Superstar Award                                                                                      
  • 2009 GCEO Excellence Awards                                                                           
  • 2012 YLL‐NUS Role Model Teacher’s Award                                                   
  • 2013 Distinguished Mentor Award (SingHealth Excellence Awards)
  • 2013 Senior Mentor Award at the People’s Choice Awards
  • YLL Dean’s Award for Teaching Excellence AY12/13, AY13/14, AY2018/2019 
  • 2015 YLL Special Recognition Award
  • 2016 Outstanding Asean Paediatrician Award
  • 2021 YLL-NUS Special Recognition Award
  • 2022 Quality Service Award (Gold)

Leadership positions / roles in Education: 

  • 2007 – Todate Adjunct Professor, YLL, NUS
  • 2016 – Todate Emeritus Consultant, KKH, Singhealth
  • 2012 – Todate Clinical Professor, Duke NUS
  • 2017 – Todate Adjunct Professor, LKC NTU

Research Interests:

  • Rotavirus Vaccine
  • Diarrhea in Children
  • Epidemiology of Rotavirus Diarrhea
  • Intussusception
  • Cholestatic Jaundice in Infancy

Selected Publications:

Parenteral Alimentation in Management of Malignant Diarrhoea
HB Wong, KB Phua
J Singapore Paed Soc 1973; 15:1

Biliary Atresia: making the diagnosis by the gallbladder ghost triad
APA Tan Kendrick, KB Phua, BC Ooi, CEL Tan
Pediatr Radiol (2003) 33:311‐315

Evaluation of RIX4414, a Live Attenuated Rotavirus Vaccine, in a Randomized, Double‐blind, Placebo‐Controlled Phase 2 Trial involving 2464 Singaporean Infants.
KB Phua, SH Quak, BW Lee, SC Emanuel, P Goh, HH Han, B De Vos, HL Bock 
The Journal of Infectious Diseases 2005, September, 102:S6‐16

Live Attenuated Human Rotavirus Vaccine (RotarixTM) 
KB Phua, N Tan
Medical Progress, May 2007 34:5:241‐8

Immunogenicity, reactogenicity and safety of a diphtheria‐tetanus‐acellular pertussis‐inactivated polio and Haemophilus influenzae Type b vaccine in a placebo‐controlled rotavirus vaccine study.
Phua KB, Quak SH, Lim FS, Goh P, Teoh YL, Datta SK, Han HH, Bock HL
Ann Acad Med Singapore 2008 Jul;37(7):546‐53

Safety and efficacy of human rotavirus vaccine during the first 2 years of life in Asian infants: randomised, double‐blind, controlled study
Phua KB, Lim FS, Lau YL, Nelson EA, Huang LM, Quak SH, Lee BW, Teoh YL, Tang H, Boudville I, Oostvogels LC, Suryakiran PV, Smolenov IV, Han HH, Bock HL
Vaccine. 2009 October 9;27(43):5936‐41

Rotavirus vaccine RIX4414 efficacy sustained during the third year of life: A randomized clinical trial in an Asian population
Kong Boo Phua, Fong Seng Lim, Yu Lung Lau, Edmund Anthony Severn Nelson, Li Min Huang, Seng Hock Quak, Bee Wah Lee, Leen Jan van Doorn, Yee Leong Teoh, Haiwen Tang, P.V. Suryakiran, Igor V. Smolenov, Hans L. Bock, Htay Htay Han
Vaccine.2012 June 22; 30(30): 4552‐7

Seventeen years of Kasai portoenterostomy for biliary atresia in a single Southeast Asian Paediatric Centre
Chiang LW, Lee CY, Krishnaswamy G, Nah SA, Kader A, Ong C, Low Y, Phua KB
J Paediatr Child Health, 2017 Apr;53(4):412‐415

Rapid rise in the incidence and clinical characteristics of paediatric inflammatory bowel disease in a South‐East Asian cohort in Singapore, 1994‐2015
Ong C, Aw MM, Liwanag M, Quak SH, Phua KB
J Dig Dis 2018 July; 19(7) 395-403

Comparing monovalent and combination hepatitis B vaccine outcome in children delivered by mothers with chronic hepatitis B
Lee LY, Chan SM, Ong C, M Aw M, Wong G, Saw S, Lee GH, Thoon KC, Phua KB
J Paediatr Child Health. 2019 Mar;55(3):327-332

Non-Invasive Predictors for the First Variceal Hemorrhage in Children With Biliary Atresia After Kasai Portoenterostomy 
Chiou FK, Ong C, Low Y, Chiang LW, Phua KB
J Clin Exp Hepatol. 2019 Sep-Oct;9(5):581-587

Survey Of Pathogens In Pediatric Diarrhea Patients Attending 
A Women’s And Children’s hospital In Singapore
ML Chau, M Maiwald, NWS Tee, M Yap, SHP Hartantyo, KT Aung, 
K Ranka, KB Phua, RA Gutiérrez, T Barkham, LC Ng
Southeast Asian J Trop Med Public Health 2019;50(4),729-741

Heterozygous missense variant in EIF6 gene: A novel form of Shwachman–Diamond syndrome?
Ai Ling Koh, Carine Bonnard, Jiin Ying Lim, Woei Kang Liew, Koh Cheng Thoon, Terrence Thomas, Nur Ain Binte Ali, Alvin Yu Jin Ng, Sumanty Tohari, Kong Boo Phua, Byrappa Venkatesh, Bruno Reversade, Saumya Shekhar Jamuar
Am J Med Genet. 2020;1–11

Analysis of cholangitis rates with extended perioperative antibiotics and adjuvant corticosteroids in biliary atresia
Lynette Goh, Kong Boo Phua, Yee Low, Li Wei Chiang, Fang Kuan Chiou  
Pediatr Gastroenterol Hepatol Nut 2021 July; 24(4):366-376