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Chew Tsong Huey, Sophia

Clinical Associate Professor

Deputy Vice Chair, Research, Anaesthesiology & Perioperative Sciences Academic Clinical Programme


Education Qualifications: MBBS, MMed (Anaes), FANZCA, FAMS

Dr Chew Tsong Huey, Sophia is a Senior Consultant with the Department of Anaesthesiology, Singapore General Hospital.  She is also a Senior Consultant with the Department of Cardiothoracic Anaesthesia, National Heart Centre Singapore.

Her subspecialty interest is in the field of cardiothoracic anaesthesia and she leads the department efforts in research. 

Dr. Chew is the Principal Investigator of the Perioperative and Genomic Outcome Study of Cardiac Patients in Singapore. She is currently examining the impact of cardiopulmonary bypass and acute kidney injury and the impact of diabetes mellitus on the outcome of patients undergoing cardiac surgery.


Professional Appointments and Committee Memberships:

  • Visiting Consultant, National Heart Centre Singapore 
  • Director of Research, Department of Anaesthesiology
  • Member, Singapore Society of Anaesthesiologists
  • Member, Medical Protection Society


  • Awarded the FY 1996 HMDP fellowship in cardiac anaesthesia for 12 months, U.S.A.
  • Completed cardiac fellowship program at Duke University Medical Center, Division of Cardiothoracic Anesthesiology, Durham, North Carolina (1997-1998) 
  • Awarded the runner-up prize on poster presentation “Preliminary report on the association of Apolipoprotein E genotype and renal impairment after CABG surgery” at Dukes Department of Anesthesiology Academic Evening (1998)
  • SGH QI Project of the year 2009 ( To achieve blood glucose level of between 4 to 8 mmol/l in patients undergoing cardiac surgery )
  • MOH Appreciation Excel Award nominee (2009) 
  • PS21 Excel Award Nominee (2009)
  • Wong Hock Boon Society-Singapore Medical Association Outstanding Mentor Award (2013) 

Research Interests:

Diabetes mellitus and outcome in cardiac surgical patients
The association of genetics and diabetes mellitus on acute kidney injury after cardiac surgery
Ethnicity and acute kidney injury in cardiac surgery
Impact of mini CPB and conventional CPB in determining safety outcomes after cardiac surgery
Development of continuous glucose monitoring devices
Improvement of diabetic control in surgical patients
Acute kidney injury and development of end-stage renal disease in cardiac surgical patients
Blood conservation in cardiac surgical patients.

Selected Publications:

Chew STH, Tan SS, Ip C, Tan T. A survey of patients knowledge of anaesthesia and perioperative care. Singapore Medical Journal. 1998; 39(9): 399-402.

Chew STH, Low TC. Preoperative versus postoperative pethidine for extraction of impacted third molars. Annals, Academy of Medicine. 1997; 26: 426-429.

Garduno C, Chew S, Forbess J, Smith PK, Grocott HP. Persistent left superior vena cava and partial anomalous pulmonary venous connection: incidental diagnosis by transeophageal echocardiography during coronary bypass surgery. J Am SocEchocardiogr. 1999; 12: 682-685.

Chew S. Renal transplant- An Anaesthetic Perspective. Proceedings. 1997; 6(3): 52-55.

Chew STH, Conlon PJ, White WD, et al. Preliminary report on the association of apolipoprotein E genotype with renal impairment after coronary bypass surgery. Anesthesiology. 2000; 93: 325-331.

Koh LKD, Ip-Yam C, Kong CF, Chew S. Evaluation of a modified grading system for direct laryngoscopy. ourpreliminary experience in Singapore. SGH Proceedings. 2000. 9(2): 79-82.

Kong CF, Chew STH, Ip-Yam PC. Intravenous opioids reduce airway irritation during induction of anaesthesia with desflurane in adults. Br J Anaesth. 2000; 84: 364–367.

McCreath BJ, Swaminathan M, Booth VJ, Chew STH et al. Mitral valve surgery and renal injury . Port access versus median sternotomy. Annals Thorac Surg. 2003; 75: 812-819

Chew STH. Recovery following tonsillectomy. A comparison between tramadol and morphine for analgesia . Singapore Medical Journal. 2003; 44(6): 296- 298

Soh CR, Pietrobon R, Freiberger J, et al. Hyperbaric oxygen therapy in necrotising soft-tissue infections – A study of patients in the United States Nationwide Inpatient Sample. Intensive Care Med. 2012; 38(7): 1143-1151. doi: 10.1007/s00134-012-2558-4.

Chew STH, Mar WMT, Lian T. Association of ethnicity and acute kidney injury after cardiac surgery in a South East Asian Population. British Journal of Anaesthesia. 2013; 110(3): 397-401. doi: 10.1093/bja/aes415.

Ng R, Chew STH, Weiling L, Kah TL. Identification of Modifiable Risk Factors for Acute Kidney Injury After Coronary Artery Bypass Graft Surgery in an Asian Population. JTCVS. 2013; 13: 833R1. doi: 10.1016/j.jtcvs.2013.09.040.

Chew STH, Kah TL. Reply to the editor on association of ethnicity and acute kidney injury after cardiac surgery in a South east Asian population. British journal of Anaesthesia. 2013. doi: 10.1093/bja/aes415.

Ng R, Chew STH, Weiling L, Kah TL. Reply to Identification of Modifiable Risk Factors for Acute Kidney Injury After Coronary Artery Bypass Graft Surgery in an Asian Population. JTCVS.2014. doi: 10.1016/j.jtcvs.2013.09.040.

Ng R, Chew STH, Weiling L, Kah TL. Persistent Kidney Injury at Hospital discharge after cardiac surgery with cardiopulmonary bypass in patients with normal preoperative serum creatinine and normal estimated glomerular filtration rate. JCVA.2014. doi: 10.1053/j.jvca.2014.05.007.
16. Ng R, Oo AM, Weiling L, Tan TE, Kah TL, Chew STH. Changing Glucose Control target and Risk of Surgical Site Infection in a South East Asian population. JTCVS. 2014.