Directory

Talent Development Fund

SingHealth,2006

NMRC Hong Leong Foundation Medical Research Scientist Award

NMRC Hong Leong Foundation,2005

14th ASM Young Scientist Award

Singapore General Hospital,2003

Application of phage display for T-cell receptor discovery.

Biotechnology advances – Ch'ng Angela Chiew Wen; Lam Paula; Alassiri Mohammed; Lim Theam Soon (2022)

54

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.

Nature communications – Newman Jennifer P; Wang Grace Y; Arima Kazuhiko; Guan Shou P; Waters Michael R; Cavenee Webster K; Pan Edward; Aliwarga Edita; Chong Siao T; Kok Catherine Y L; Endaya Berwini B; Habib Amyn A; Horibe Tomohisa; Ng Wai H; Ho Ivy A W; Hui Kam M; Kordula Tomasz; Lam Paula Y P (2017)

8 (1);

Recent discoveries concerning the tumor - mesenchymal stem cell interactions.

Biochimica et biophysica acta – Lazennec Gwendal; Lam Paula Y (2016)

1866 (2); 290-299

Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling.

Oncotarget – Endaya Berwini; Guan Shou P; Newman Jennifer P; Huynh Hung; Sia Kian C; Chong Siao T; Kok Catherine Y L; Chung Alexander Y F; Liu Bin B; Hui Kam M; Lam Paula Y P (2017)

8 (33); 54629-54639

Paracrine factors of human fetal MSCs inhibit liver cancer growth through reduced activation of IGF-1R/PI3K/Akt signaling.

Molecular therapy : the journal of the American Society of Gene Therapy – Yulyana Yulyana; Ho Ivy A W; Sia Kian Chuan; Newman Jennifer P; Toh Xin Yi; Endaya Berwini B; Chan Jerry K Y; Gnecchi Massimiliano; Huynh Hung; Chung Alexander Y F; Lim Kiat Hon; Leong Hui Sun; Iyer Narayanan Gopalakrishna; Hui Kam Man; Lam Paula Y P (2015)

23 (4); 746-56

Matrix metalloproteinase-1-mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C-X-C chemokine receptor 4 axis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology – Ho Ivy A W; Yulyana Yulyana; Sia Kian C; Newman Jennifer P; Guo Chang M; Hui Kam M; Lam Paula Y P (2014)

28 (10); 4359-68

The potential application of a transcriptionally regulated oncolytic herpes simplex virus for human cancer therapy

British Journal of Cancer – Lv M, Fraefel C, Sia KC, Newman JP, Shafiq Ali Bin Mohamed Bashir , Ng WH and Lam PY  (2014)

110 94-106

Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.

Molecular cancer therapeutics – Sia Kian Chuan; Huynh Hung; Chung Alexander Yaw Fui; Ooi London Lucien Peng Jin; Lim Kiat Hon; Hui Kam Man; Lam Paula Yeng Po (2013)

12 (8); 1651-64

Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis.

Stem cells (Dayton, Ohio) – Ho Ivy A W; Toh Han C; Ng Wai H; Teo Yuan L; Guo Chang M; Hui Kam M; Lam Paula Y P (2013)

31 (1); 146-55

Suicidal gene therapy in the effective control of primary human hepatocellular carcinoma as monitored by noninvasive bioimaging.

Gene therapy – Sia K C; Huynh H; Chinnasamy N; Hui K M; Lam P Y P (2012)

19 (5); 532-42

Targeting human glioma cells using HSV-1 amplicon peptide display vector.

Gene therapy – Ho I A W; Miao L; Sia K C; Wang G Y; Hui K M; Lam P Y P (2010)

17 (2); 250-60

Matrix metalloproteinase 1 is necessary for the migration of human bone marrow-derived mesenchymal stem cells toward human glioma.

Stem cells (Dayton, Ohio) – Ho Ivy A W; Chan Kelly Y W; Ng Wai-Hoe; Guo Chang M; Hui Kam M; Cheang Philip; Lam Paula Y P (2009)

27 (6); 1366-75

An Efficient and Safe Herpes Simplex Virus Type 1 Amplicon Vector for Transcriptionally Targeted Therapy of Human Hepatocellular Carcinomas.

Molecular therapy : the journal of the American Society of Gene Therapy – Lam Paula Yp; Sia Kian Chuan; Khong Jenn H; Geest Bart De; Lim Kar S; Ho Ivy Aw; Wang Grace Y; Miao Lv; Huynh H; Hui Kam M (2007)

15 (6); 1129-1136

Engineering an improved cell cycle-regulatable herpes simplex virus type 1 amplicon vector with enhanced transgene expression in proliferating cells yet attenuated activities in resting cells.

Human gene therapy – Wang Grace Y; Ho Ivy A W; Sia Kian C; Miao L; Hui Kam M; Lam Paula Y P (2007)

18 (3); 222-31

A microarray study to characterize the molecular mechanism of TIMP-3-mediated tumor rejection.

Molecular therapy : the journal of the American Society of Gene Therapy – Lam Paula; Sian Lim Kar; Mei Wang Suk; Hui Kam M (2005)

12 (1); 144-52

Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.

Human gene therapy – Lam Paula; Hui Kam M; Wang Yaming; Allen Paul D; Louis David N; Yuan C J; Breakefield Xandra O (2002)

13 (18); 2147-59

Potential of gene therapy for brain tumors.

Human molecular genetics – Lam P Y; Breakefield X O (2001)

10 (7); 777-87

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

Molecular and cellular biology – Lam P Y; Sublett J E; Hollenbach A D; Roussel M F (1999)

19 (1); 594-601

Pax3 modulates expression of the c-Met receptor during limb muscle development.

Proceedings of the National Academy of Sciences of the United States of America – Epstein J A; Shapiro D N; Cheng J; Lam P Y; Maas R L (1996)

93 (9); 4213-8

Pax3 inhibits myogenic differentiation of cultured myoblast cells.

The Journal of biological chemistry – Epstein J A; Lam P; Jepeal L; Maas R L; Shapiro D N (1995)

270 (20); 11719-22