ABOUT THE LECTURE:We generated a single-cell multiomic atlas of the developing
human neocortex, defining cellular composition, spatial organization, lineage
trajectories, and disease risk. Our data identifies novel progenitor lineages and gene regulatory
networks, informs glioblastoma and neuropsychiatric mechanisms, and guides derivation of
specific neural cell types. These insights enabled generation of inhibitory interneurons
now in clinical testing for refractory temporal lobe epilepsy.
HOST:
Prof Wang Hongyan
Acting Programme Director
Neuroscience & Behavioural Disorders Programme
Duke-NUS Medical School
VENUE:
Duke-NUS Medical School
Meeting Room 7C, Level 7
CONTACT PERSON:
Ms Kathleen Chan (kathleen.chan@duke-nus.edu.sg)
Duke-NUS Research Affairs Department
Date and Time
27 Mar 2026 @ 12:00 - 27 Mar 2026 @ 13:00
Speaker
Prof Arnold Kriegstein
Professor
Department of Neurology
University of California San Francisco (UCSF)
After graduating Yale University, Dr. Kriegstein earned his
MD and PhD from New York University and completed neurology residency at
Harvard. Following faculty positions at Stanford, Yale, and Columbia, he joined
UCSF in 2004, where he founded the Broad Stem Cell Center. He is a member of the National Academy of
Medicine. His research focuses on the stem cell niche, how neural stem and progenitor cells
produce neurons in the developing brain, and the relation to neurodevelopmental
diseases.